Meet the people who are changing the future

Kristin MacDonald Every so often you hear a story and your first reaction is “oh, I have to share this with someone, anyone, everyone.” That’s what happened to me the other day. I was talking with Kristin MacDonald, an amazing woman, a fierce patient advocate and someone who took part in a CIRM-funded clinical trial … Continue reading Meet the people who are changing the future

Stem Cell All-Stars, All For You

Dr. Larry Goldstein, UC San Diego It’s not often you get a chance to hear some of the brightest minds around talk about their stem cell research and what it could mean for you, me and everyone else. That’s why we’re delighted to be bringing some of the sharpest tools in the stem cell shed … Continue reading Stem Cell All-Stars, All For You

Therapy developed with CIRM award used in new clinical trial for COVID-19

Dr. Joshua Rhein, Assistant Professor of Medicine in the University of Minnesota Medical School's Division of Infectious Diseases and International Medicine Image Credit: University of Minnesota While doctors are still trying to better understand how to treat some of the most severe cases of COVID-19, researchers are looking at their current scientific "toolkit" to see if … Continue reading Therapy developed with CIRM award used in new clinical trial for COVID-19

Super charging killer cells to fight leukemia

Colorized scanning electron micrograph of a natural killer cell.Photo credit: National Institute of Allergy and Infectious Diseases Racing car drivers are forever tinkering with their cars, trying to streamline them and soup up their engines because while fast is good, faster is better. Researchers do the same things with potential anti-cancer therapies, tinkering with them … Continue reading Super charging killer cells to fight leukemia

Blocking pancreatic cancer stem cells

John Cashman Cancer stem cells are one of the main reasons why cancers are able to survive surgery, chemotherapy and radiation. They are able to hide from those therapies and, at a future date, emerge and spread the cancer in the body once again. Jionglia Cheng, PhD. Jionglia Cheng, PhD., the lead author of a … Continue reading Blocking pancreatic cancer stem cells

You can bank on CIRM

Way back in 2013, the CIRM Board invested $32 million in a project to create an iPSC Bank. The goal was simple;  to collect tissue samples from people who have different diseases, turn those samples into high quality stem cell lines - the kind known as induced pluripotent stem cells (iPSC) - and create a … Continue reading You can bank on CIRM

CIRM-funded trial for blood cancer releases promising new data

A CIRM-funded trial conducted by Oncternal Therapeutics in collaboration with UC San Diego released an interim clinical data update for patients with mantle cell lymphoma (MCL), a type of blood cancer. The treatment being developed involves an antibody called cirmtuzumab (named after yours truly) being used with a cancer fighting drug called ibrutinib. The antibody … Continue reading CIRM-funded trial for blood cancer releases promising new data

New CAR-T cell therapy using scorpion venom developed to treat brain tumors

Contributed by Wikimedia Commons (Public Domain) Glioblastoma (GBM) is an aggressive form of cancer that begins in the brain and results in tumors that can be very difficult to treat. This condition has claimed the lives of Beau Biden, former Vice President Joe Biden's son, and John McCain, former Senator of Arizona. However, a new … Continue reading New CAR-T cell therapy using scorpion venom developed to treat brain tumors

Big time validation for early support

It’s not every day that a company and a concept that you helped support from the very beginning gets snapped up for $4.9 billion. But that’s what is happening with Forty Seven Inc. and their anti-cancer therapies. Gilead, another California company by the way, has announced it is buying Forty Seven Inc. for almost $5 … Continue reading Big time validation for early support

Breakthrough image could lead to better therapies

Image of a blood stem cell in its natural environment: Photo courtesy UC Merced When it comes to using stem cells for therapy you don’t just need to understand what kinds of cell to use, you also need to understand the environment that is best for them. Trying to get stem cells to grow in … Continue reading Breakthrough image could lead to better therapies