It’s been almost ten years since the voters of California created the Stem Cell Agency when they overwhelmingly approved Proposition 71, providing us $3 billion to help fund stem cell research. In the last ten years we have made great progress – we will have ten projects that we are funding in or approved to … Continue reading What everybody needs to know about CIRM: where has the money gone
Cancer
From Stem Cells to Stomachs: Scientists Generate 3D, Functioning Human Stomach Tissue
The human stomach can be a delicate organ. For example, even the healthiest stomach can be compromised by H. pylori bacteria—a tiny but ruthless pathogen which has shown to be linked to both peptic ulcer disease and stomach cancer. The best way to study how an H. pylori infection leads to conditions like cancer would … Continue reading From Stem Cells to Stomachs: Scientists Generate 3D, Functioning Human Stomach Tissue
Scientists Develop Stem Cell ‘Special Forces’ in order to Target, Destroy Brain Tumors
Curing someone of cancer is, in theory, a piece of cake: all you have to do is kill the cancer cells while leaving the healthy cells intact. But in practice, this solution is far more difficult. In fact, it remains one of the great unsolved problems in modern oncology: how do you find, target and … Continue reading Scientists Develop Stem Cell ‘Special Forces’ in order to Target, Destroy Brain Tumors
CIRM-Funded Scientists Make New Progress Toward Engineering a Human Esophagus
Creating tissues and organs from stem cells—often referred to as ‘tissue engineering’—is hard. But new research has discovered that the process may in fact be a little easier than we once thought, at least in some situations. Last week, scientists at The Saban Research Institute of Children’s Hospital Los Angeles announced that the esophagus—the tube … Continue reading CIRM-Funded Scientists Make New Progress Toward Engineering a Human Esophagus
Cells’ Knack for Hoarding Proteins Inadvertently Kickstarts the Aging Process
Even cells need to take out the trash in order to maintain a healthy clean environment. And scientists are now uncovering the harmful effects when cells instead begin to hoard their garbage. Aging, on the cellular level is—at its core—the increasing inability for cells to repair themselves over time. As cells begin to break down … Continue reading Cells’ Knack for Hoarding Proteins Inadvertently Kickstarts the Aging Process
New Cellular Tracking Device Tests Ability of Cell-Based Therapies to Reach Intended Destination
Therapies aimed at replacing damaged cells with a fresh, healthy batch hold immense promise—but there remains one major sticking point: once you have injected new, healthy cells into the patient, how do you track them and how do you ensure they do the job for which they were designed? Unfortunately, there’s no easy solution. The … Continue reading New Cellular Tracking Device Tests Ability of Cell-Based Therapies to Reach Intended Destination
Harder, Better, Faster, Stronger: Scientists Work to Create Improved Immune System One Cell at a Time
The human immune system is the body’s best defense against invaders. But even our hardy immune systems can sometimes be outpaced by particularly dangerous bacteria, viruses or other pathogens, or even by cancer. But what if we could give our immune system a boost when it needs it most? Last week scientists at the Salk … Continue reading Harder, Better, Faster, Stronger: Scientists Work to Create Improved Immune System One Cell at a Time
Stem cell stories that caught our eye: first iPS clinical trial, cancer metabolism and magnates helping heal hearts
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. First clinical trial with reprogrammed stem cells. Today, a Japanese woman became the first patient to be treated with cells derived from reprogrammed iPS-type stem … Continue reading Stem cell stories that caught our eye: first iPS clinical trial, cancer metabolism and magnates helping heal hearts
Stories of Hope: Leukemia
This week on The Stem Cellar we feature some of our most inspiring patients and patient advocates as they share, in their own words, their Stories of Hope. Stem cells create life. But if things go wrong, they can also threaten it. Theresa Blanda found that out the hard way. Fortunately for her, CIRM-funded research … Continue reading Stories of Hope: Leukemia
CIRM-Funded Scientists Test Recipe for Building New Muscles
When muscles get damaged due to disease or injury, the body activates its reserves—muscle stem cells that head to the injury site and mature into fully functioning muscle cells. But when the reserves are all used up, things get tricky. This is especially the case for people living with muscle diseases, such as muscular dystrophy, … Continue reading CIRM-Funded Scientists Test Recipe for Building New Muscles
The Stem Cellar 