It’s not an easy thing to bring an entire Board of Directors to tears, but four extraordinary people and their families managed to do just that at the last CIRM Board meeting of 2016. The four are patients who have undergone life-saving or life-changing stem cell therapies that were funded by our agency. The … Continue reading Stem cell heroes: patients who had life-saving, life-changing treatments inspire CIRM Board
Cancer
How stem cells are helping change the face of medicine, one pioneering patient at a time
One of the many great pleasures of my job is that I get to meet so many amazing people. I get to know the researchers who are changing the face of medicine, but even more extraordinary are the people who are helping them do it, the patients. Attacking Cancer It’s humbling to meet people like … Continue reading How stem cells are helping change the face of medicine, one pioneering patient at a time
Stem cell stories that caught our eye: Horse patients, Brain cancer stem cells, and a Bony Heart
Horsing around at the World Stem Cell Summit The World Stem Cell Summit (WSCS) is coming up very shortly (December 6-9) in lovely downtown West Palm Beach, Florida. And this year it has an added attraction; horses. For my money the WSCS is the most enjoyable of the many conferences held around the US focusing … Continue reading Stem cell stories that caught our eye: Horse patients, Brain cancer stem cells, and a Bony Heart
Stem cell agency funds clinical trials in three life-threatening conditions
A year ago the CIRM Board unanimously approved a new Strategic Plan for the stem cell agency. In the plan are some rather ambitious goals, including funding ten new clinical trials in 2016. For much of the last year that has looked very ambitious indeed. But today the Board took a big step towards reaching … Continue reading Stem cell agency funds clinical trials in three life-threatening conditions
Stem cell stories that caught our eye: Blood stem cells on a diet, Bladder control after spinal cord injuries, new ALS insights
Putting blood stem cells on a diet. (Karen Ring) Scientists from Stanford and the University of Tokyo have figured out a new way to potentially make bone marrow transplants more safe. Published yesterday in the journal Science, the teams discovered that removing an essential amino acid, called valine, from the diets of mice depleted their … Continue reading Stem cell stories that caught our eye: Blood stem cells on a diet, Bladder control after spinal cord injuries, new ALS insights
Buildup of random mutations in adult stem cells doesn’t explain varying frequency of cancers
To divide or not to divide? It’s a question every cell in your body must constantly ask itself. Cells in your small intestine, for instance, replace themselves about every three days so the cells in that tissue must divide frequently to replenish the tissue. Liver cell are less active and turn over about once a … Continue reading Buildup of random mutations in adult stem cells doesn’t explain varying frequency of cancers
Stem cell stories that caught our eye: Salamander limb regrowth, mass producing cells for kidneys and halting cancer stem cells
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Fun with axolotls. Axolotls, the albino aquatic critters that look like they have feathers growing out of the backs of their heads, have long been … Continue reading Stem cell stories that caught our eye: Salamander limb regrowth, mass producing cells for kidneys and halting cancer stem cells
Sleep inducing hormone puts breast cancer cells to rest
It’s pretty easy to connect the dots between a lack of sleep and an increased risk of a deadly car crash. But what about an increased risk of cancer? A 2012 study of 101 women newly diagnosed with breast cancer found that those with inadequate sleep were more likely to have more aggressive tumors. Though … Continue reading Sleep inducing hormone puts breast cancer cells to rest
Stem cell stories that caught our eye: screening for cancer drugs for kids, better CRISPR gene editing and funding for chimeras
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Stem cells screen drugs for kids’ rare tumor. A team at Johns Hopkins University in Baltimore has transformed stem cells into a particularly nasty form … Continue reading Stem cell stories that caught our eye: screening for cancer drugs for kids, better CRISPR gene editing and funding for chimeras
T cell fate and future immunotherapies rely on a tag team of genetic switches
Imagine if scientists could build microscopic smart missiles that specifically seek out and destroy deadly, hard-to-treat cancer cells in a patient’s body? Well, you don’t have to imagine it actually. With techniques such as chimeric antigen receptor (CAR) T therapy, a patient’s own T cells – immune system cells that fight off viruses and cancer … Continue reading T cell fate and future immunotherapies rely on a tag team of genetic switches