Buildup of random mutations in adult stem cells doesn’t explain varying frequency of cancers

To divide or not to divide?  It’s a question every cell in your body must constantly ask itself. Cells in your small intestine, for instance, replace themselves about every three days so the cells in that tissue must divide frequently to replenish the tissue. Liver cell are less active and turn over about once a … Continue reading Buildup of random mutations in adult stem cells doesn’t explain varying frequency of cancers

From Pig Parts to Stem Cells: Scientist Douglas Melton Wins Ogawa-Yamanaka Prize for Work on Diabetes

Since the 1920s, insulin injections have remained the best solution for managing type 1 diabetes. Patients with this disease do not make enough insulin – a hormone that regulates the sugar levels in your blood – because the insulin-producing cells, or beta cells, in their pancreas are destroyed. Back then, it took two tons of … Continue reading From Pig Parts to Stem Cells: Scientist Douglas Melton Wins Ogawa-Yamanaka Prize for Work on Diabetes

Stem cell stories that caught our eye: healing diabetic ulcers, new spinal cord injury insights & an expanding CRISPR toolbox

Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Stem cells heal diabetic foot ulcers in pilot study Foot ulcers are one of the many long-term complications that diabetics face. About 15 percent of … Continue reading Stem cell stories that caught our eye: healing diabetic ulcers, new spinal cord injury insights & an expanding CRISPR toolbox

Gene required for sperm stem cells linked to male infertility, UCSD study suggests

Even in this day and age, when a couple is having trouble conceiving a child, it’s often the woman who is initially suspected of having infertility problems and is likely the first to seek out the advice of doctor. But according to Miles Wilkinson, professor of reproductive medicine at UC San Diego School of Medicine, … Continue reading Gene required for sperm stem cells linked to male infertility, UCSD study suggests

Stem Cell Experts Discuss the Ethical Implications of Translating iPSCs to the Clinic

Part of The Stem Cellar blog series on 10 years of iPSCs. This year, scientists are celebrating the 10-year anniversary of Shinya Yamanaka’s Nobel Prize winning discovery of induced pluripotent stem cells (iPSCs). These are cells that are very similar biologically to embryonic stem cells and can develop into any cell in the body. iPSCs … Continue reading Stem Cell Experts Discuss the Ethical Implications of Translating iPSCs to the Clinic

Full Steam Ahead: First Patient is Dosed in Expanded CIRM Spinal Cord Injury Trial

Today we bring you more good news about a CIRM-funded clinical trial for spinal cord injury that’s received a lot of attention lately in the news. Asterias Biotherapeutics has treated its first patient in an expanded patient population of spinal cord injury patients who suffer from cervical, or neck, injuries. In late August, Asterias reported … Continue reading Full Steam Ahead: First Patient is Dosed in Expanded CIRM Spinal Cord Injury Trial

Stem cell stories that caught our eye: two studies of the heart and cool stem cell art

Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Understanding Heart Defects. Healthy heart tissue is made up of smooth, solid muscle, which is essential for normal heart function. Patients with a heart defect … Continue reading Stem cell stories that caught our eye: two studies of the heart and cool stem cell art

Funding stem cell research targeting a rare and life-threatening disease in children

If you have never heard of cystinosis you should consider yourself fortunate. It’s a rare condition caused by an inherited genetic mutation. It hits early and it hits hard. Children with cystinosis are usually diagnosed before age 2 and are in end-stage kidney failure by the time they are 9. If that’s not bad enough … Continue reading Funding stem cell research targeting a rare and life-threatening disease in children

Faulty fat stem cells & obesity-related diabetes

You see it in the news all the time: more and more people around the world are obese and as a result they’re at a higher risk for diabetes, heart disease and cancer. In fact, 90% of individuals with type 2 diabetes are overweight or obese. “Healthy” obese individuals protected from diabetes and other complications … Continue reading Faulty fat stem cells & obesity-related diabetes

CIRM Grantees Reflect on Ten Years of iPS Cells

For the fourth entry for our “Ten Years of Induced Pluripotent Stem (iPS) Cells” series, which we’ve been posting all month, I reached out to three of our CIRM grantees to get their perspectives on the impact of iPSC technology on their research and the regenerative medicine field as a whole: Step back in time … Continue reading CIRM Grantees Reflect on Ten Years of iPS Cells