It was a very CIRMy news week on both the clinical trial and discovery research fronts. Here are some the highlights: Stanford cancer-fighting spinout to Genentech: 'Don't eat me' – San Francisco Business Times Ron Leuty, of the San Francisco Business Times, reported this week on not one, but two news releases from CIRM grantee … Continue reading Stem Cell RoundUp: CIRM Clinical Trial Updates & Mapping Human Brain
Cell Type
How Tom Howing turned to stem cells to battle back against a deadly cancer
As we enter the new year, CIRM’s 2017 Annual Report will be posted in less than two weeks! Here’s one of the people we are profiling in the report, a patient who took part in a CIRM-funded clinical trial. In March of 2015, Tom Howing was diagnosed with stage 4 cancer. Over the next 18 … Continue reading How Tom Howing turned to stem cells to battle back against a deadly cancer
CHLA study explains how stem cells slow progression of kidney disorder
Not all stem cell-based therapies act by replacing diseased or damaged cells. Many treatments in clinical development rely on the injected stem cells releasing proteins which trigger the slow down or even reversal of damage caused by disease or injury. A new CIRM-funded study that’s developing a stem cell therapy for a rare kidney disease … Continue reading CHLA study explains how stem cells slow progression of kidney disorder
UCLA scientists on track to develop a stem cell replacement therapy for Duchenne Muscular Dystrophy
Last year, we wrote about a CIRM-funded team at UCLA that’s on a mission to develop a stem cell treatment for patients with Duchenne muscular dystrophy (DMD). Today, we bring you an exciting update on this research just in time for the holidays (Merry Christmas and Happy Hanukkah and Kwanza to our readers!). DMD is … Continue reading UCLA scientists on track to develop a stem cell replacement therapy for Duchenne Muscular Dystrophy
Stem Cell Stories that Caught Our Eye: GPS for Skin & Different Therapies for Aging vs. Injured Muscles?
Skin stem cells specialize into new skin by sensing neighborhood crowding When embarking on a road trip, the GPS technology inside our smartphones helps us know where we are and how to get where we’re going. The stem cells buried in the deepest layers of our skin don’t have a GPS and yet, they do … Continue reading Stem Cell Stories that Caught Our Eye: GPS for Skin & Different Therapies for Aging vs. Injured Muscles?
A new study suggests CRISPR gene editing therapies should be customized for each patient
You know a scientific advance is a big deal when it becomes the main premise and title of a Jennifer Lopez-produced TV drama. That’s the case for CRISPR, a revolutionary gene-editing technology that promises to yield treatments for a wide range of genetic diseases. In fact, clinical trials using the CRISPR method are already underway … Continue reading A new study suggests CRISPR gene editing therapies should be customized for each patient
Using the AIDS virus to help children battling a deadly immune disorder
More than 35 million people around the world have been killed by HIV, the virus that causes AIDS. So, it’s hard to think that the same approach the virus uses to infect cells could also be used to help children battling a deadly immune system disorder. But that’s precisely what researchers at UC San Francisco … Continue reading Using the AIDS virus to help children battling a deadly immune disorder
CIRM interviews Lorenz Studer: 2017 recipient of the Ogawa-Yamanaka Stem Cell Prize [Video]
For eight long years, researchers who were trying to develop a stem cell-based therapy for Parkinson’s disease – an incurable movement disorder marked by uncontrollable shaking, body stiffness and difficulty walking – found themselves lost in the proverbial wilderness. In initial studies, rodent stem cells were successfully coaxed to specialize into dopamine-producing nerve cells, the … Continue reading CIRM interviews Lorenz Studer: 2017 recipient of the Ogawa-Yamanaka Stem Cell Prize [Video]
Comparing two cellular reprogramming methods from one donor’s cells yields good news for iPSCs
In 2012, a mere six years after his discovery of induced pluripotent stem cells (iPSCs), Shinya Yamanaka was awarded the Nobel Prize in Medicine. Many Nobel winners aren’t recognized until decades after their initial groundbreaking studies. That goes to show you the importance of Yamanaka’s technique, which can reprogram a person’s cells, for example skin … Continue reading Comparing two cellular reprogramming methods from one donor’s cells yields good news for iPSCs
Hey, what’s the big idea? CIRM Board is putting up more than $16.4 million to find out
When you have a life-changing, life-threatening disease, medical research never moves as quickly as you want to find a new treatment. Sometimes, as in the case of Parkinson’s disease, it doesn’t seem to move at all. At our Board meeting last week David Higgins, our Board member and Patient Advocate for Parkinson’s disease, made that … Continue reading Hey, what’s the big idea? CIRM Board is putting up more than $16.4 million to find out