Chronic myelogenous leukemia Chronic myelogenous leukemia (CML) is a cancer of the white blood cells. It causes them to increase in number, crowd out other blood cells, leading to anemia, infection or heavy bleeding. Up until the early 2000’s the main weapon against CML was chemotherapy, but the introduction of drugs called tyrosine kinase inhibitors … Continue reading CIRM funded research could lead to treatment to prevent recurrence of deadly blood cancer
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Rare Disease, Type 1 Diabetes, and Heart Function: Breakthroughs for Three CIRM-Funded Studies
This past week, there has been a lot of mention of CIRM funded studies that really highlight the importance of the work we support and the different disease areas we make an impact on. This includes important research related to rare disease, Type 1 Diabetes (T1D), and heart function. Below is a summary of the … Continue reading Rare Disease, Type 1 Diabetes, and Heart Function: Breakthroughs for Three CIRM-Funded Studies
Engineered T cells made from stem cells could provide immunity against multiple cancers
Dr. Lily Yang Within all of our bodies there is a special type of "super" immune cell that holds enormous potential. Unlike regular immune cells that can only attack one cancer at a time, these "super" immune cells have the ability to target many types of cancers at once. These specialized cells are known as … Continue reading Engineered T cells made from stem cells could provide immunity against multiple cancers
“Brains” in a dish that can create electrical impulses
Brain organoids in a petri dish: photo courtesy UCSD For several years, researchers have been able to take stem cells and use them to make three dimensional structures called organoids. These are a kind of mini organ that scientists can then use to study what happens in the real thing. For example, creating kidney organoids … Continue reading “Brains” in a dish that can create electrical impulses
Boosting the blood system after life-saving therapy
Following radiation, the bone marrow shows nearly complete loss of blood cells in mice (left). Mice treated with the PTP-sigma inhibitor displayed rapid recovery of blood cells (purple, right): Photo Courtesy UCLA Chemotherapy and radiation are two of the front-line weapons in treating cancer. They can be effective, even life-saving, but they can also be … Continue reading Boosting the blood system after life-saving therapy
Drug used to treat multiple sclerosis may improve glioblastoma outcomes
Dr. Jeremy Rich, UC San Diego Glioblastoma is an aggressive form of cancer that invades brain tissue, making it extremely difficult to treat. Current therapies involving radiation and chemotherapy are effective in destroying the bulk of brain cancer cells, but they are not able to reach the brain cancer stem cells, which have the ability … Continue reading Drug used to treat multiple sclerosis may improve glioblastoma outcomes
Stem cell progress and promise in fighting leukemia
Computer illustration of a cancerous white blood cell in leukemia. There is nothing you can do to prevent or reduce your risk of leukemia. That’s not a very reassuring statement considering that this year alone almost 62,000 Americans will be diagnosed with leukemia; almost 23,000 will die from the disease. That’s why CIRM is funding … Continue reading Stem cell progress and promise in fighting leukemia
CIRM-Funded Researchers Develop Chimeric “Mighty Mouse” Model to Study Alzheimer’s Disease
Dr. Mathew Blurton-Jones, leader of team that developed the chimeric "Mighty Mouse" model at the University of California, Irvine In ancient Greek mythology, a Chimera was a creature that was usually depicted as a lion with an additional goat head and a serpent for a tail. Due to the Chimera's animal hybrid nature, the term … Continue reading CIRM-Funded Researchers Develop Chimeric “Mighty Mouse” Model to Study Alzheimer’s Disease
One family’s fight to save their son’s life, and how stem cells made it possible
CIRM's mission is very simple: to accelerate stem cell treatments to patients with unmet medical needs. Anne Klein's son, Everett, was a poster boy for that statement. Born with a fatal immune disorder Everett faced a bleak future. But Anne and husband Brian were not about to give up. The following story is one Anne … Continue reading One family’s fight to save their son’s life, and how stem cells made it possible
How stem cells know the right way to make a heart . And what goes wrong when they don’t
Gladstone scientists Deepak Srivastava (left), Yvanka De Soysa (center), and Casey Gifford (right) publish a complete catalog of the cells involved in heart development. The invention of GPS navigation systems has made finding your way around so much easier, providing simple instructions on how to get from point A to point B. Now, a new … Continue reading How stem cells know the right way to make a heart . And what goes wrong when they don’t
The Stem Cellar 