A Phase 1 clinical trial co-sponsored by CIRM and Oncternal Therapeutics, has started treating patients at UC San Diego (UCSD). The goal of the trial is to test the safety and anti-tumor activity of the Oncternal-developed drug, cirmtuzumab, in treating breast cancer. Breast cancer is the second most common cancer to occur in women, regardless … Continue reading A cancer therapy developed at a CIRM Alpha Stem Cell Clinic tests its legs against breast cancer
Cancer Stem Cells
Early CIRM support helps stem cell pioneer develop promising new therapy for cancer
When you get praise from someone who has been elected to the National Academy of Sciences and has been named California Scientist of the Year you know you must be doing something right. That’s how we felt the other day when Irv Weissman, Director of the Stanford Institute of Stem Cell Biology and Regenerative Medicine, … Continue reading Early CIRM support helps stem cell pioneer develop promising new therapy for cancer
Stem Cell Roundup: Protein shows promise in treating deadliest form of breast cancer: mosquito spit primes our body for disease
Triple negative breast cancer is more aggressive and difficult to treat than other forms of the disease and, as a result, is more likely to spread throughout the body and to recur after treatment. Now a team at the University of Southern California have identified a protein that could help change that. The research, published … Continue reading Stem Cell Roundup: Protein shows promise in treating deadliest form of breast cancer: mosquito spit primes our body for disease
Therapies Targeting Cancer, Deadly Immune Disorder and Life-Threatening Blood Condition Get Almost $32 Million Boost from CIRM Board
An innovative therapy that uses a patient’s own immune system to attack cancer stem cells is one of three new clinical trials approved for funding by CIRM's Governing Board. Researchers at the Stanford University School of Medicine were awarded $11.9 million to test their Chimeric Antigen Receptor (CAR) T Cell Therapy in patients with B … Continue reading Therapies Targeting Cancer, Deadly Immune Disorder and Life-Threatening Blood Condition Get Almost $32 Million Boost from CIRM Board
Stem Cell Agency Heads to Inland Empire for Free Patient Advocate Event
I am embarrassed to admit that I have never been to the Inland Empire in California, the area that extends from San Bernardino to Riverside counties. That’s about to change. On Monday, April 16th CIRM is taking a road trip to UC Riverside, and we’re inviting you to join us. We are holding a special, … Continue reading Stem Cell Agency Heads to Inland Empire for Free Patient Advocate Event
Stem Cell Roundup: hESCs turn 20, tracking cancer stem cells, new ALS gene ID’d
Stem Cell Image of the Week This week’s stunning stem cell image is brought to you by researchers in the Brivanlou Lab at Rockefeller University. What looks like the center of a sunflower is actual a ball of neural rosettes derived from human embryonic stem cells (ESCs). Neural rosettes are structures that contain neural stem … Continue reading Stem Cell Roundup: hESCs turn 20, tracking cancer stem cells, new ALS gene ID’d
CIRM-funded clinical trial takes a combination approach to treating deadly blood cancers
A diagnosis of cancer often means a tough road ahead, with surgery, chemotherapy and radiation used to try and kill the tumor. Even then, sometimes cancer cells manage to survive and return later, spreading throughout the body. Now researchers at UC San Diego and Oncternal Therapeutics are teaming up with a combination approach they hope … Continue reading CIRM-funded clinical trial takes a combination approach to treating deadly blood cancers
California gets first royalty check from Stem Cell Agency investments
CIRM recently shared in a little piece of history. The first royalty check, based on CIRM’s investment in stem cell research, was sent to the California State Treasurer’s office from City of Hope. It’s the first of what we hope will be many such checks, helping repay, not just the investment the state made in … Continue reading California gets first royalty check from Stem Cell Agency investments
Novel approach to slowing deadly brain cancer stem cells may lead to new treatments
Glioblastoma, a form of brain cancer, is one of the most dreaded cancer diagnoses. Standard radiation and chemotherapy treatments for glioblastoma almost always prove ineffective because of the cancer’s ability to grow back. With their unlimited potential to self-renew, cancer stem cells within the brain tumor are thought to be responsible for its aggressive reoccurrence. … Continue reading Novel approach to slowing deadly brain cancer stem cells may lead to new treatments
Stem Cell RoundUp: CIRM Clinical Trial Updates & Mapping Human Brain
It was a very CIRMy news week on both the clinical trial and discovery research fronts. Here are some the highlights: Stanford cancer-fighting spinout to Genentech: 'Don't eat me' – San Francisco Business Times Ron Leuty, of the San Francisco Business Times, reported this week on not one, but two news releases from CIRM grantee … Continue reading Stem Cell RoundUp: CIRM Clinical Trial Updates & Mapping Human Brain