One family’s fight to save their son’s life, and how stem cells made it possible

CIRM's mission is very simple: to accelerate stem cell treatments to patients with unmet medical needs. Anne Klein's son, Everett, was a poster boy for that statement. Born with a fatal immune disorder Everett faced a bleak future. But Anne and husband Brian were not about to give up. The following story is one Anne … Continue reading One family’s fight to save their son’s life, and how stem cells made it possible

From bench to bedside: a Q&A with stem cell expert Jan Nolta

At CIRM we are privileged to work with many remarkable people who combine brilliance, compassion and commitment to their search for new therapies to help people in need. One of those who certainly fits that description is UC Davis' Jan Nolta. This week the UC Davis Newsroom posted a great interview with Jan. Rather than … Continue reading From bench to bedside: a Q&A with stem cell expert Jan Nolta

Developing a non-toxic approach to bone-crushing cancers

When cancer spreads to the bone the results can be devastating Battling cancer is always a balancing act. The methods we use – surgery, chemotherapy and radiation - can help remove the tumors but they often come at a price to the patient. In cases where the cancer has spread to the bone the treatments … Continue reading Developing a non-toxic approach to bone-crushing cancers

“A new awakening”: One patient advocate’s fight for her daughters life

We often talk about the important role that patient advocates play in helping advance research. That was demonstrated in a powerful way last week when the CIRM Board approved almost $12 million to fund a clinical trial targeting a rare childhood disorder called cystinosis. The award, to Stephanie Cherqui and her team at UC San … Continue reading “A new awakening”: One patient advocate’s fight for her daughters life

CIRM Board Approves New Clinical Trial for Rare Childhood Disease

Today the governing Board of the California Institute for Regenerative Medicine (CIRM) approved a grant of almost $12 million to Dr. Stephanie Cherqui at the University of California, San Diego (UCSD) to conduct a clinical trial for treatment of cystinosis. This award brings the total number of CIRM funded clinical trials to 55.  Cystinosis is … Continue reading CIRM Board Approves New Clinical Trial for Rare Childhood Disease

Stanford study successful in transplant of mismatched stem cells, tissue in mice

Dr. Irv Weissman at Stanford University A transplant can be a lifesaving procedure for many people across the United States. In fact, according to the Health Resources & Services Administration, 36,528 transplants were performed in 2018. However, as of January 2019, the number of men, women, and children on the national transplant waiting list is … Continue reading Stanford study successful in transplant of mismatched stem cells, tissue in mice

Stanford and University of Tokyo researchers crack the code for blood stem cells

Blood stem cells grown in lab Blood stem cells offer promise for a variety of immune and blood related disorders such as sickle cell disease and leukemia. Like other stem cells, blood stem cells have the ability to generate additional blood stem cells in a process called self-renewal. Additionally, they are able to generate blood … Continue reading Stanford and University of Tokyo researchers crack the code for blood stem cells

How a see-through fish could one day lead to substitutes for bone marrow transplants

Human blood stem cells For years researchers have struggled to create human blood stem cells in the lab. They have done it several times with animal models, but the human kind? Well, that’s proved a bit trickier. Now a CIRM-funded team at UC San Diego (UCSD) think they have cracked the code. And that would … Continue reading How a see-through fish could one day lead to substitutes for bone marrow transplants

CIRM Board Approves Funding for New Clinical Trials in Solid Tumors and Pediatric Disease

Dr. Theodore Nowicki, physician in the division of pediatric hematology/oncology at UCLA. Photo courtesy of Milo Mitchell/UCLA Jonsson Comprehensive Cancer Center The governing Board of the California Institute for Regenerative Medicine (CIRM) awarded two grants totaling $11.15 million to carry out two new clinical trials.  These latest additions bring the total number of CIRM funded … Continue reading CIRM Board Approves Funding for New Clinical Trials in Solid Tumors and Pediatric Disease

CIRM & NHLBI Create Landmark Agreement on Curing Sickle Cell Disease

CIRM Board approves first program eligible for co-funding under the agreement Adrienne Shapiro, co-founder of Axis Advocacy, with her daughter Marissa Cors, who has Sickle Cell Disease. Sickle Cell disease (SCD) is a painful, life-threatening blood disorder that affects around 100,000 people, mostly African Americans, in the US. Even with optimal medical care, SCD shortens … Continue reading CIRM & NHLBI Create Landmark Agreement on Curing Sickle Cell Disease