Ronnie, a boy who was born without a functioning immune system but who is thriving today because of CIRM funded research When CIRM was created in 2004 the field of stem cell research was still very much in its infancy. Fast forward 15 years and it’s moving ahead at a rapid pace, probably faster than … Continue reading The Past, the Present, and the Uncertain Future of Stem Cell Research
Basic Research
Advancing stem cell research in many ways
Speakers at the Alpha Stem Cell Clinics Network Symposium: Photo by Marco Sanchez From Day One CIRM’s goal has been to advance stem cell research in California. We don’t do that just by funding the most promising research -though the 51 clinical trials we have funded to date clearly shows we do that rather well … Continue reading Advancing stem cell research in many ways
Muscle stem cells provide insight into treatment of muscular dystrophies and aging muscles
Dr. Alessandra Sacco, associate professor in the Development, Aging and Regeneration Program at Sanford Burnham Prebys. Muscles are a vital part of the body that enable us to walk, run, lift, and do everyday activities. When muscles start to deteriorate, we start to have difficulty performing these activities, which severely limits quality of life and … Continue reading Muscle stem cells provide insight into treatment of muscular dystrophies and aging muscles
New model unlocks clues to treating deadly childhood cancer
CIRM-funded research at Sanford Burnham Prebys Medical Discovery Institute in San Diego is identifying compounds that could be used to help children battling a deadly brain cancer. The cancer is choroid plexus carcinoma (CPC), a rare brain tumor that occurs mainly in children. As it grows the tumor can affect nearby parts of the brain … Continue reading New model unlocks clues to treating deadly childhood cancer
Organoids revolutionize approach to studying a variety of diseases
Organoids There are limitations to studying cells under a microscope. To understand some of the more complex processes, it is critical to see how these cells behave in an environment that is similar to conditions in the body. The production of organoids has revolutionized this approach. Organoids are three-dimensional structures derived from stem cells that … Continue reading Organoids revolutionize approach to studying a variety of diseases
Rats, research and the road to new therapies
Don Reed Don Reed has been a champion of CIRM even before there was a CIRM. He's a pioneer in pushing for funding for stem cell research and now he's working hard to raise awareness about the difference that funding is making. In a recent article on Daily Kos, Don highlighted one of the less … Continue reading Rats, research and the road to new therapies
Of Mice and Men, and Women Too; Stem cell stories you might have missed
Mice brains can teach us a lot Last week’s news headlines were dominated by one big story, the use of a stem cell transplant to effectively cure a person of HIV. But there were other stories that, while not quite as striking, did also highlight how the field is advancing. A new way to boost … Continue reading Of Mice and Men, and Women Too; Stem cell stories you might have missed
Mending Stem Cells: The Past, Present and Future of Regenerative Medicine
To Mend: (verb used with object) to make (something broken, worn, torn or otherwise damaged) whole, sound or usable by repairing. It’s remarkable to believe, but today doctors literally have the tools to repair damaged cells. These tools are being used to treat people with diseases that were once incurable. The field of regenerative medicine has made tremendous … Continue reading Mending Stem Cells: The Past, Present and Future of Regenerative Medicine
Stories that caught our eye: National Geographic takes a deep dive into iPS cells; Japanese researchers start iPS cell clinical trial for spinal cord injury; and do high fat diets increase your risk of colorectal cancer
Can cell therapy beat the most difficult diseases? That’s the question posed in a headline in National Geographic. The answer; maybe, but it is going to take time and money. The article focuses on the use of iPS cells, the man-made equivalent of embryonic stem cells that can be turned into any kind of cell … Continue reading Stories that caught our eye: National Geographic takes a deep dive into iPS cells; Japanese researchers start iPS cell clinical trial for spinal cord injury; and do high fat diets increase your risk of colorectal cancer
A new stem cell derived tool for studying brain diseases
Sergiu Pasca’s three-dimensional culture makes it possible to watch how three different brain-cell types – oligodendrocytes (green), neurons (magenta) and astrocytes (blue) – interact in a dish as they do in a developing human brain. Courtesy of the Pasca lab Neurological diseases are among the most daunting diagnoses for a patient to receive, because they … Continue reading A new stem cell derived tool for studying brain diseases
The Stem Cellar 