Why is a cell therapy that restores sight to the blind against the law?

A lot of people are frustrated with the US Food and Drug Administration (FDA) and its woefully slow process for approving stem cell therapies. That’s one of the reasons why we started the CIRM Stem Cell Champions campaign, to gather as many like-minded supporters of stem cell research as possible and help to change the … Continue reading Why is a cell therapy that restores sight to the blind against the law?

What’s the big idea? Or in this case, what’s the 19 big ideas?

Have you ever stood in line in a supermarket checkout line and browsed through the magazines stacked conveniently at eye level? (of course you have, we all have). They are always filled with attention-grabbing headlines like “5 Ways to a Slimmer You by Christmas” or “Ten Tips for Rock Hard Abs” (that one doesn’t work … Continue reading What’s the big idea? Or in this case, what’s the 19 big ideas?

A Dream made me change my mind. Almost.

Dream Alliance: photo courtesy Daily Telegraph, UK On Friday I was faced with the real possibility that a horse had made an ass out of me. Over the years we have written many articles about the risks of unproven stem cell therapies, treatments that have not yet been shown in clinical trials to be safe … Continue reading A Dream made me change my mind. Almost.

Approach that inspires DREADD could create new way to treat Parkinson’s disease

Dopamine producing brain nerve cells, made from embryonic stem cells Imagine having a treatment for Parkinson’s that acts like a light switch, enabling you to turn it on or off depending on your needs. Well, that’s what researchers at the University of Wisconsin-Madison have come up with. And if it works, it might help change … Continue reading Approach that inspires DREADD could create new way to treat Parkinson’s disease

Brave new world or dark threatening future: a clear-eyed look at genome editing and what it means for humanity

   Is this the face of the future? “Have you ever wished that there were something different about yourself? Maybe you imagined yourself taller, thinner or stronger? Smarter? More attractive? Healthier?” That’s the question posed by UC Davis stem cell researcher (and CIRM grantee) Paul Knoepfler at the start of his intriguing new book ‘GMO … Continue reading Brave new world or dark threatening future: a clear-eyed look at genome editing and what it means for humanity

A visual guide on using stem cells to treat blindness

Some stories are so sweet or powerful or wonderful - or all three - that they just stick in your mind. About 18 months ago Rosalinda and German Barrero came to talk to the CIRM Board about retinitis pigmentosa (RP), a devastating genetic disease that slowly destroys a person’s vision. Contrary to what everyone expected … Continue reading A visual guide on using stem cells to treat blindness

New study says stem cells derived from older people may have more problems than we thought.

Ever since 2006 when Japanese researcher Shinya Yamanaka showed that you could take an adult cell, such as those in your skin, and reprogram it to act like an embryonic stem cell, the scientific world has looked at these induced pluripotent stem (iPS) cells as a potential game changer. They had the ability to convert … Continue reading New study says stem cells derived from older people may have more problems than we thought.

Patient Advocates find their voice in a different language

Packed house for stem cell conference in Tokyo - Adrienne Shapiro front row, second from right One of the many wonderful things about travel is that it opens up your eyes and mind to the fact that, while there are many ways in which people around the world differ from each other, there are also … Continue reading Patient Advocates find their voice in a different language

How do you know what patients want if you never even ask them?

Our mission at CIRM is to accelerate stem treatments to patients with unmet medical needs. But what if those needs are not just unmet, they’re also unknown? What happens when those developing treatments never even bother to ask those they are trying to help if this is what they really need, or want? The question … Continue reading How do you know what patients want if you never even ask them?

How to handle CRISPR: Formulating a responsible approach to gene-editing

In February 2016, CIRM sponsored a workshop to discuss the impact of CRISPR, a gene-editing tool that is transforming stem cell research. The workshop was designed to enable the Standards Working Group  (SWG) to reflect on policies governing the review and oversight of embryo research support by CIRM. After the workshop, we wrote a blog … Continue reading How to handle CRISPR: Formulating a responsible approach to gene-editing