To Mend: (verb used with object) to make (something broken, worn, torn or otherwise damaged) whole, sound or usable by repairing. It’s remarkable to believe, but today doctors literally have the tools to repair damaged cells. These tools are being used to treat people with diseases that were once incurable. The field of regenerative medicine has made tremendous … Continue reading Mending Stem Cells: The Past, Present and Future of Regenerative Medicine
UCSD
CIRM-funded clinical trial takes a combination approach to treating deadly blood cancers
A diagnosis of cancer often means a tough road ahead, with surgery, chemotherapy and radiation used to try and kill the tumor. Even then, sometimes cancer cells manage to survive and return later, spreading throughout the body. Now researchers at UC San Diego and Oncternal Therapeutics are teaming up with a combination approach they hope … Continue reading CIRM-funded clinical trial takes a combination approach to treating deadly blood cancers
Scientists repair spinal cord injuries in monkeys using human stem cells
An exciting development for spinal cord injury research was published this week in the journal Nature Medicine. Scientists from the University of San Diego School of Medicine transplanted human neural progenitor cells (NPCs) into rhesus monkeys that had spinal cord injuries. These cells, which are capable of turning into other cells in the brain, survived … Continue reading Scientists repair spinal cord injuries in monkeys using human stem cells
Harnessing the body’s immune system to tackle cancer
Often on the Stem Cellar we write about work that is in a clinical trial. But getting research to that stage takes years and years of dedicated work. Over the next few months, we are profiling some of the scientists we fund who are doing Discovery (early stage) and Translational (pre-clinical) research, to highlight the … Continue reading Harnessing the body’s immune system to tackle cancer
Scientists find switch that targets immunotherapies to solid tumors
Cancer immunotherapies harness the power of the patient’s own immune system to fight cancer. One type of immunotherapy, called adoptive T cell therapy, uses immune cells called CD8+ Killer T cells to target and destroy tumors. These T cells are made in the spleen and lymph nodes and they can migrate to different locations in … Continue reading Scientists find switch that targets immunotherapies to solid tumors
Confusing cancer to kill it
Confusion is not a state of mind that we usually seek out. Being bewildered is bad enough when it happens naturally, so why would anyone actively pursue it? But now some researchers are doing just that, using confusion to not just block a deadly blood cancer, but to kill it. Today the CIRM Board approved … Continue reading Confusing cancer to kill it
Stem Cell Stories That Caught Our Eye: Plasticity in the pancreas and two cool stem cell tools added to the research toolbox
There’s more plasticity in the pancreas than we thought. You’re taught a lot of things about the world when you’re young. As you get older, you realize that not everything you’re told holds true and it’s your own responsibility to determine fact from fiction. This evolution in understanding happens in science too. Scientists do research … Continue reading Stem Cell Stories That Caught Our Eye: Plasticity in the pancreas and two cool stem cell tools added to the research toolbox
One scientist’s quest to understand autism using stem cells
April is National Autism Awareness Month and people and organizations around the world are raising awareness about a disorder that affects more than 20 million people globally. Autism affects early brain development and causes a wide spectrum of social, mental, physical and emotional symptoms that appear during childhood. Because the symptoms and their severity can … Continue reading One scientist’s quest to understand autism using stem cells
A Clinical Trial Network Focused on Stem Cell Treatments is Expanding
Geoff Lomax is a Senior Officer of CIRM's Strategic Initiatives. California is one of the world-leaders in advancing stem cell research towards treatments and cures for patients with unmet medical needs. California has scientists at top universities and companies conducting cutting edge research in regenerative medicine. It also has CIRM, California’s Stem Cell Agency, which … Continue reading A Clinical Trial Network Focused on Stem Cell Treatments is Expanding
Funding stem cell research targeting a rare and life-threatening disease in children
If you have never heard of cystinosis you should consider yourself fortunate. It’s a rare condition caused by an inherited genetic mutation. It hits early and it hits hard. Children with cystinosis are usually diagnosed before age 2 and are in end-stage kidney failure by the time they are 9. If that’s not bad enough … Continue reading Funding stem cell research targeting a rare and life-threatening disease in children
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