CIRM awards $6 million to advance research for heart attack and heart failure treatments

In a promising development for cardiovascular health, Arjun Deb, MD, a professor of medicine and molecular, cell, and developmental biology at UCLA, has received a $6 million award from the California Institute for Regenerative Medicine (CIRM) to advance his groundbreaking research on heart attack and heart failure treatments. Cardiovascular disease remains the leading cause of … Continue reading CIRM awards $6 million to advance research for heart attack and heart failure treatments

CIRM at LABEST: Empowering the future of bioscience in the LA region  

The California Institute for Regenerative Medicine (CIRM) proudly participated in and sponsored the recent 2024 Los Angeles Bioscience Ecosystem Summit Twenty (LABEST) Conference, the premier showcase for bioscience innovation in Los Angeles.   With around 1,000 participants, LABEST is one of the largest gatherings of visionary scientists, enthusiastic entrepreneurs, and pioneering institutions in the region.   Top … Continue reading CIRM at LABEST: Empowering the future of bioscience in the LA region  

CIRM invests $1.5 million to UCLA for research identifying risk factors for viral infections

Image of Michael Wells, PhD from UCLA The California Institute for Regenerative Medicine (CIRM) recently awarded $1.5 million to a new research project led by Michael Wells, PhD, of UCLA, that aims to identify the genetic and molecular risk factors underlying disease-causing viral infections in multiple diverse ancestral populations. Dr. Wells and his team of … Continue reading CIRM invests $1.5 million to UCLA for research identifying risk factors for viral infections

CIRM Board Approves Funding for New Clinical Trial Targeting Brain Tumors

The governing Board of the California Institute for Regenerative Medicine (CIRM) has awarded almost $12 million to carry out a clinical trial targeting brain tumors. This brings the total number of CIRM funded clinical trials to 83.   $11,999,984 was awarded to Dr. Jana Portnow at the Beckman Research Institute of City of Hope. They are using Neural stem … Continue reading CIRM Board Approves Funding for New Clinical Trial Targeting Brain Tumors

California researchers developing vaccine to curb the spread of Zika virus

Zika is caused by a virus that is mainly transmitted by infected female Aedes aegypti mosquitoes but also through sexual intercourse. People infected by Zika virus usually have mild symptoms that normally last for two to seven days and can include fever, skin rashes, conjunctivitis, muscle and joint pain, or headaches. Zika also causes devastating … Continue reading California researchers developing vaccine to curb the spread of Zika virus

A better, faster, more effective way to edit genes

Clinical fellow Brian Shy talks with postdoctoral scholar Tori Yamamoto in the Marson Lab at Gladstone Institutes on June 8th, 2022. Photo courtesy Gladstone Institutes. For years scientists have been touting the potential of CRISPR, a gene editing tool that allows you to target a specific mutation and either cut it out or replace it … Continue reading A better, faster, more effective way to edit genes

UCLA-led team creates first comprehensive map of human blood stem cell development

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Human blood stem cells emerging from specialized endothelial cells in the wall of an embryonic aorta. UCLA scientists’ confirmation of this process clarifies a longstanding controversy about the stem cells’ cellular origin. Image Credit: Hanna Mikkola Lab/UCLA, Katja Schenke-Layland Lab/University of Tübingen, Nature California researchers from … Continue reading UCLA-led team creates first comprehensive map of human blood stem cell development

Chance discovery could lead to a treatment for skin ulcers

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Dr. Antoni Ribas in his research lab on the UCLA Campus: Photo courtesy Ann Johansson When UCLA's Dr. Antoni Ribas was researching a potential therapy for melanoma, a form of skin cancer, he stumbled upon something unexpected. That unexpected discovery has now resulted in him getting … Continue reading Chance discovery could lead to a treatment for skin ulcers

CIRM Board gives thumbs up to training and treatment programs

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST CIRM Bridges student discusses her poster presentation At CIRM, the bread and butter of what we do is funding research and hopefully advancing therapies to patients. But the jam, that's our education programs. Helping train the next generation of stem cell and gene therapy scientists is … Continue reading CIRM Board gives thumbs up to training and treatment programs

UCLA gene therapy offers children with LAD-1 a new chance at living a normal life

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Photo courtesy of Tamara Hogue/UCLA Broad Stem Cell Research Center Leukocyte adhesion deficiency type 1 (LAD-1) is a rare pediatric disorder that causes the immune system to malfunction, resulting in recurrent, often severe, bacterial and fungal infections as well as delayed wound healing. This is because of a missing protein that would normally … Continue reading UCLA gene therapy offers children with LAD-1 a new chance at living a normal life