There is no singular cause of Parkinson’s disease, but many—making this disease so difficult to understand and, as a result, treat. But now, researchers at the Buck Institute for Research on Aging have tracked down precisely how a genetic change, or mutation, can lead to a common form of the disease. The results, published last … Continue reading Mutation Morphs Mitochondria in Models of Parkinson’s Disease, CIRM-Funded Study Finds
iPS cells
Stem cell stories that caught our eye; progress toward artificial brain, teeth may help the blind and obesity
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. More progress toward artificial brain. A team at the RIKEN Institute in Japan has used stem cells in a 3-D culture to create brain tissue … Continue reading Stem cell stories that caught our eye; progress toward artificial brain, teeth may help the blind and obesity
MIT Scientists Recreate Malaria in a Dish to Test Promising Drug Candidates
At the beginning, it feels like the flu: aches, pains and vomiting. But then you begin to experience severe cold and shivering, followed by fever and sweating—a cycle, known as tertian fever, that repeats itself every two days. And that’s when you know: you’ve contracted malaria. But you wouldn’t be alone. According to the World … Continue reading MIT Scientists Recreate Malaria in a Dish to Test Promising Drug Candidates
Stem cell stories that caught our eye: new ways to reprogram, shifting attitudes on tissue donation, and hockey legend’s miracle questioned
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Insulin-producing cells produced from skin. Starting with human skin cells a team at the University of Iowa has created iPS-type stem cells through genetic reprogramming … Continue reading Stem cell stories that caught our eye: new ways to reprogram, shifting attitudes on tissue donation, and hockey legend’s miracle questioned
CIRM-funded scientists track the steps that take an adult cell back in time
The ability to transform an adult cell back into a stem cell has been heralded as one of the greatest achievements of the 21st century. Scientists have lauded this discovery, made by Nobel Prize-winning scientist Shinya Yamanaka, as a game changer for the future of medicine. Despite this extraordinary advance, the method remains inefficient. And … Continue reading CIRM-funded scientists track the steps that take an adult cell back in time
Peering inside the brain: how stem cells could help turn skin into therapies for dementia
To truly understand a disease you need to be able to see how it works, how it causes our body to act in ways that it shouldn’t. In cancer, for example, you can take cells from a tumor and observe them under a microscope to see what is going on. But with diseases of the … Continue reading Peering inside the brain: how stem cells could help turn skin into therapies for dementia
Creating a Genetic Model for Autism, with a Little Help from the Tooth Fairy
One of the most complex aspects of autism is that it is not one disease—but many. Known more accurately as the autism spectrum disorder, or ASD, experts have long been trying to tease apart the various ways in which the condition manifests in children, with limited success. But now, using the latest stem cell technology, … Continue reading Creating a Genetic Model for Autism, with a Little Help from the Tooth Fairy
Harder, Better, Faster, Stronger: Scientists Work to Create Improved Immune System One Cell at a Time
The human immune system is the body’s best defense against invaders. But even our hardy immune systems can sometimes be outpaced by particularly dangerous bacteria, viruses or other pathogens, or even by cancer. But what if we could give our immune system a boost when it needs it most? Last week scientists at the Salk … Continue reading Harder, Better, Faster, Stronger: Scientists Work to Create Improved Immune System One Cell at a Time
What a Difference Differentiation can Make: a Little Change can Reduce the Risk of Rejection
No one likes to be rejected. It hurts. But while rejection is something most of us experience at least a couple of times in our life, researchers at Stanford have found a way to reduce the risk of rejection, at least when it comes to one form of stem cells. Reporting in the latest issue … Continue reading What a Difference Differentiation can Make: a Little Change can Reduce the Risk of Rejection