Yanhong Shi, Ph.D., City of Hope Canavan disease is a fatal neurological disorder, the most prevalent form of which begins in infancy. It is caused by mutation of the ASPA gene, resulting in the deterioration of white matter (myelin) in the brain and preventing the proper transmission of nerve signals. The mutated ASPA gene causes … Continue reading CIRM-funded development of stem cell therapy for Canavan disease shows promising results
induced pluripotent stem cells
CIRM Bridges program prepared student for research of a rare disease
Ian Blong, Ph.D., CIRM San Francisco State University Bridges to Stem Cell Research Alumnus Recently, The New York Times released a powerful article that tells the stories of four different families navigating the challenges of having a family member with a rare disease. One of these stories focused on Matt Wilsey, a tech entrepreneur and … Continue reading CIRM Bridges program prepared student for research of a rare disease
Scientists at UC Davis discover a way to help stem cells repair heart tissue
Researchers Phung Thai (left) and Padmini Sirish were part of a research team seeking stem cell solutions to heart failure care. Image Credit: UC Davis Repairing the permanent damage associated with a heart attack or long-term heart disease has been a challenge that scientists have been trying to tackle for a long time. Heart failure … Continue reading Scientists at UC Davis discover a way to help stem cells repair heart tissue
Therapy developed with CIRM award used in new clinical trial for COVID-19
Dr. Joshua Rhein, Assistant Professor of Medicine in the University of Minnesota Medical School's Division of Infectious Diseases and International Medicine Image Credit: University of Minnesota While doctors are still trying to better understand how to treat some of the most severe cases of COVID-19, researchers are looking at their current scientific "toolkit" to see if … Continue reading Therapy developed with CIRM award used in new clinical trial for COVID-19
Researchers 3D print a heart pump using stem cells
This image used on the cover of the American Heart Association’s Circulation Research journal is a 3D rendering of the printed heart pump developed at the University of Minnesota. The discovery could have major implications for studying heart disease. Credit: Kupfer, Lin, et al., University of Minnesota According to the Centers for Disease Control and Prevention (CDC), heart … Continue reading Researchers 3D print a heart pump using stem cells
CIRM Board Approves Two Discovery Research Projects for COVID-19
Dr. Steven Dowdy (left), Dr. Evan Snyder (center), and Dr. John Zaia (right) This past Friday the governing Board of the California Institute for Regenerative Medicine (CIRM) approved two additional discovery research projects as part of the $5 million in emergency funding for COVID-19 related projects. This brings the number of COVID-19 projects CIRM is supporting to … Continue reading CIRM Board Approves Two Discovery Research Projects for COVID-19
Stem cells used to look at how COVID-19 attacks heart muscle
Human induced pluripotent stem cell-derived cardiomyocytes (heart cells) shown in green and blue, are infected by the novel coronavirus SARS-CoV-2 (red). Image provided by Cedars-Sinai Board of Governors Regenerative Medicine Institute. There is still a lot that we don't understand about SARS-CoV-2 (COVID-19), the new coronavirus that has caused a worldwide pandemic. Some patients that … Continue reading Stem cells used to look at how COVID-19 attacks heart muscle
CIRM Board Approves Third Clinical Trial for COVID-19
Dr. Xiaokui Zhang (left), Dr. Albert Wong (center), and Dr. Preet Chaudhary (right) Today the governing Board of the California Institute for Regenerative Medicine (CIRM) awarded $750,000 to Dr. Xiaokui Zhang at Celularity to conduct a clinical trial for the treatment of COVID-19. This brings the total number of CIRM clinical trials to 64, including … Continue reading CIRM Board Approves Third Clinical Trial for COVID-19
Stem cells used to promote quick and precise bone healing
A close-up view of the intricate microarchitecture of the pluripotent stem-cell-derived extracellular matrix. Image Credit: Carl Gregory/Texas A&M Although some broken bones can be mended with the help of a cast, others require more complex treatments. Bone grafts, which can come from the patient's own body or a donor, are used to transplant bone tissue … Continue reading Stem cells used to promote quick and precise bone healing
“Mini” human liver made of stem cells successfully transplanted in rats
Miniature liver made from human skin cells turned stem cells turned specialized liver cells Photo Credit: University of Pittsburgh School of Medicine According to the American Liver Foundation website, almost 14,000 patients are on the waiting list for a liver transplant. But what if there was a way to generate a liver using your own … Continue reading “Mini” human liver made of stem cells successfully transplanted in rats
The Stem Cellar 