CIRM funded study uses drug development in a dish for treatment of heart arrhythmias

Image Credit: Center for Disease Control and Prevention (CDC) Cardiac (heart) arrhythmias occur when electrical impulses that coordinate your heartbeats don't work properly, causing your heart to beat too fast, too slow, or in an irregular manner. In the U.S. alone, almost one million individuals are hospitalized every year for heart arrhythmias. Close to 300,000 … Continue reading CIRM funded study uses drug development in a dish for treatment of heart arrhythmias

De-stressing stem cells and the Bonnie & Clyde of stem cells

Dr. John Cashman The cells in our body are constantly signalling with each other, it's a critical process by which cells communicate not just with other cells but also with elements within themselves. One of the most important signalling pathways is called Wnt. This plays a key role in early embryonic and later development. But … Continue reading De-stressing stem cells and the Bonnie & Clyde of stem cells

Scientists create “drug-like” chemical that may inhibit pancreatic cancer stem cells

John R. Cashman, Ph.D. Supreme Court justice Ruth Bader Ginsburg's death this past week after battling stage 4 pancreatic cancer is a grim reminder of how aggressive the disease can be. In fact, pancreatic cancer will soon be the second leading cause of cancer-related death for individuals in the United States. Unfortunately, it is known … Continue reading Scientists create “drug-like” chemical that may inhibit pancreatic cancer stem cells

Precision guided therapy from a patient’s own cells

Dr. Wesley McKeithan, Stanford Imagine having a tool you could use to quickly test lots of different drugs against a disease to see which one works best. That’s been a goal of stem cell researchers for many years but turning that idea into a reality hasn’t been easy. That may be about to change. A … Continue reading Precision guided therapy from a patient’s own cells

Blocking pancreatic cancer stem cells

John Cashman Cancer stem cells are one of the main reasons why cancers are able to survive surgery, chemotherapy and radiation. They are able to hide from those therapies and, at a future date, emerge and spread the cancer in the body once again. Jionglia Cheng, PhD. Jionglia Cheng, PhD., the lead author of a … Continue reading Blocking pancreatic cancer stem cells