An illustration of a macrophage, a vital part of the immune system, engulfing and destroying a cancer cell. Antibody 5F9 blocks a "don't eat me" signal emitted from cancer cells. Courtesy of Forty Seven, Inc. Myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) are both types of blood cancers that can be difficult to treat. CIRM … Continue reading CIRM funded clinical trial shows promising results for patients with blood cancers
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Stanford and University of Tokyo researchers crack the code for blood stem cells
Blood stem cells grown in lab Blood stem cells offer promise for a variety of immune and blood related disorders such as sickle cell disease and leukemia. Like other stem cells, blood stem cells have the ability to generate additional blood stem cells in a process called self-renewal. Additionally, they are able to generate blood … Continue reading Stanford and University of Tokyo researchers crack the code for blood stem cells
Stem Cell Agency Board Approves New Clinical Trial for Type 1 Diabetes
Dr. Peter Stock at the capitol in Sacramento in May 2016. Photo courtesy of Steve German. Today the governing Board of the California Institute for Regenerative Medicine (CIRM) awarded $11.08 Million to Dr. Peter Stock at the University of California San Francisco (UCSF) to conduct a clinical trial for treatment of Type 1 Diabetes (T1D). … Continue reading Stem Cell Agency Board Approves New Clinical Trial for Type 1 Diabetes
Stem cell model reveals deeper understanding into “ALS resilient” neurons
A descriptive illustration of Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's Disease. Courtesy of ALS Foundation website. Understanding the basic biology of how a cell functions can be crucial to being able to better understand a disease and unlock a potential approach for a treatment. Stem cells are unique in that they give … Continue reading Stem cell model reveals deeper understanding into “ALS resilient” neurons
3D brain model shows potential for treatment of hypoxic brain injuries in infants
Image of 3D brain cultures in the Sergiu Pasca lab. Photo courtesy of Timothy Archibald. A baby's time in the womb is one of the most crucial periods in terms of its development. The average length of gestation, which is defined as the amount of time in the womb from conception to birth, is approximately … Continue reading 3D brain model shows potential for treatment of hypoxic brain injuries in infants
The Past, the Present, and the Uncertain Future of Stem Cell Research
Ronnie, a boy who was born without a functioning immune system but who is thriving today because of CIRM funded research When CIRM was created in 2004 the field of stem cell research was still very much in its infancy. Fast forward 15 years and it’s moving ahead at a rapid pace, probably faster than … Continue reading The Past, the Present, and the Uncertain Future of Stem Cell Research
CIRM Board Approves Funding for New Clinical Trials in Solid Tumors and Pediatric Disease
Dr. Theodore Nowicki, physician in the division of pediatric hematology/oncology at UCLA. Photo courtesy of Milo Mitchell/UCLA Jonsson Comprehensive Cancer Center The governing Board of the California Institute for Regenerative Medicine (CIRM) awarded two grants totaling $11.15 million to carry out two new clinical trials. These latest additions bring the total number of CIRM funded … Continue reading CIRM Board Approves Funding for New Clinical Trials in Solid Tumors and Pediatric Disease
CIRM & NHLBI Create Landmark Agreement on Curing Sickle Cell Disease
CIRM Board approves first program eligible for co-funding under the agreement Adrienne Shapiro, co-founder of Axis Advocacy, with her daughter Marissa Cors, who has Sickle Cell Disease. Sickle Cell disease (SCD) is a painful, life-threatening blood disorder that affects around 100,000 people, mostly African Americans, in the US. Even with optimal medical care, SCD shortens … Continue reading CIRM & NHLBI Create Landmark Agreement on Curing Sickle Cell Disease
Muscle stem cells provide insight into treatment of muscular dystrophies and aging muscles
Dr. Alessandra Sacco, associate professor in the Development, Aging and Regeneration Program at Sanford Burnham Prebys. Muscles are a vital part of the body that enable us to walk, run, lift, and do everyday activities. When muscles start to deteriorate, we start to have difficulty performing these activities, which severely limits quality of life and … Continue reading Muscle stem cells provide insight into treatment of muscular dystrophies and aging muscles
Stanford scientist uses CRISPR-Cas9 and stem cells to develop potential “bubble baby” therapy
Dr. Matthew Porteus, professor of pediatrics at Stanford University. Photo courtesy of Stanford Medicine. Our immune system is an important and essential part of everyday life. It is crucial for fighting off colds and, with the help of vaccinations, gives us immunity to potentially lethal diseases. Unfortunately, for some infants, this innate bodily defense mechanism … Continue reading Stanford scientist uses CRISPR-Cas9 and stem cells to develop potential “bubble baby” therapy
The Stem Cellar 