https://open.spotify.com/episode/4IimCtQ8STpFikwZRXqSAB Dr. Rosa Bacchetta on the right with Brian Lookofsky (left) and Taylor Lookofsky after CIRM funded Dr. Bacchetta's work in October 2019. Taylor has IPEX syndrome It’s always lovely to end the week on a bright note and that’s certainly the case this week, thanks to some encouraging news about CIRM-funded research targeting blood … Continue reading Looking back and looking forward: good news for two CIRM-supported studies
Blood
Engineered bone tissue improves stem cell transplants
Bone marrow transplants are currently the only approved stem cell-based therapy in the United States. They involve replacing the hematopoietic, or blood-forming stem cells, found in the bone marrow with healthy stem cells to treat patients with cancers, immune diseases and blood disorders. For bone marrow transplants to succeed, patients must undergo radiation therapy to … Continue reading Engineered bone tissue improves stem cell transplants
Gene editing in blood stem cells just got easier
Genome editing is a field of science that’s been around for awhile, but has experienced an explosion of activity and interest in recent years. Chances are that even your grandmother has heard about the recent story where for the first time, gene editing saved a one-year-old girl from dying of leukemia. Microsoft word versus genome … Continue reading Gene editing in blood stem cells just got easier
Stem cell stories that caught our eye: cancer fighting virus, lab-grown guts work in dogs, stem cell trial to cure HIV
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Cancer fighting virus approved for melanoma (Disclaimer: While this isn’t a story about stem cells, it’s pretty cool so I had to include it.) The … Continue reading Stem cell stories that caught our eye: cancer fighting virus, lab-grown guts work in dogs, stem cell trial to cure HIV
The Stem Cell Bank is open for business
When you go to a bank and withdraw money you know that the notes you get are all going to look the same and do the same job, namely allow you to buy things. But when you get stem cells for research that’s not necessarily the case. Stem cells bought from different laboratories don’t always … Continue reading The Stem Cell Bank is open for business
Sonic Hedgehog provides pathway to fight blood cancers
For a lot of people Sonic Hedgehog is a video game. But for stem cell researcher Dr. Catriona Jamieson it is a signaling pathway in the body that offers a way to tackle and defeat some deadly blood cancers. Dr. Jamieson - a researcher at the University of California, San Diego (UCSD) - has a … Continue reading Sonic Hedgehog provides pathway to fight blood cancers
Stem Cell Stories that Caught our Eye: What’s the Best Way to Treat Deadly Cancer, Destroying Red Blood Cells’ Barricade, Profile of CIRM Scientist Denis Evseenko
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Stem Cells vs. Drugs for Treating Deadly Cancer. When dealing with a potentially deadly form of cancer, choosing the right treatment is critical. But what … Continue reading Stem Cell Stories that Caught our Eye: What’s the Best Way to Treat Deadly Cancer, Destroying Red Blood Cells’ Barricade, Profile of CIRM Scientist Denis Evseenko
Revealing the Invisible: Scientists Uncover the Secret Ingredient to Making Blood-Forming Stem Cells
They are among the most versatile types of stem cell types in the body. They live inside bone marrow and in the blood of the umbilical cord. They can be used to treat deadly cancers such as leukemia (Leukemia Fact Sheet) as well as many blood disorders. But no one really understood the details of … Continue reading Revealing the Invisible: Scientists Uncover the Secret Ingredient to Making Blood-Forming Stem Cells
Creaky Cell Machinery Affects the Aging Immune System, CIRM-Funded Study Finds
Why do our immune systems weaken over time? Why are people over the age of 60 more susceptible to life-threatening infections and many forms of cancer? There’s no one answer to these questions—but scientists at the University of California, San Francisco (UCSF), have uncovered an important mechanism behind this phenomenon. Reporting in the latest issue … Continue reading Creaky Cell Machinery Affects the Aging Immune System, CIRM-Funded Study Finds
Stem cell stories that caught our eye: young blood, cord blood, and blood cancers
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Pinning down young blood’s rejuvenating power. A trio of studies in the past week provided more evidence that giving older mice the blood of younger … Continue reading Stem cell stories that caught our eye: young blood, cord blood, and blood cancers