Stem cell-based gut-on-a-chip: a new path to personalized medicine

“Personalized medicine” is a trendy phrase these days, frequently used in TV ads for hospitals, newspaper articles about medicine’s future and even here in the Stem Cellar. The basic gist is that by analyzing a patient’s unique biology, a physician can use disease treatments that are most likely to work in that individual. This concept … Continue reading Stem cell-based gut-on-a-chip: a new path to personalized medicine

In a stem cell first, functioning human kidney structures grown in living animals

One of the ultimate quests in the stem cell field – growing organs to repair diseased or damaged ones – took a significant step forward this week. In a first, researchers at the University of Manchester, in the U.K., showed that human embryonic stem cell-derived kidney tissue forms into functional kidney structures, capable of filtering … Continue reading In a stem cell first, functioning human kidney structures grown in living animals

Harnessing DNA as a programmable instruction kit for stem cell function

DNA is the fundamental molecule to all living things. The genetic sequences embedded in its double-helical structure contain the instructions for producing proteins, the building blocks of our cells. When our cells divide, DNA readily unzips into two strands and makes a copy of itself for each new daughter cell. In a Nature Communications report … Continue reading Harnessing DNA as a programmable instruction kit for stem cell function

Stem cell stories that caught our eye: spinal cord injury trial update, blood stem cells in lungs, and using parsley for stem cell therapies

More good news on a CIRM-funded trial for spinal cord injury. The results are now in for Asterias Biotherapeutics’ Phase 1/2a clinical trial testing a stem cell-based therapy for patients with spinal cord injury. They reported earlier this week that six out of six patients treated with 10 million AST-OPC1 cells, which are a type … Continue reading Stem cell stories that caught our eye: spinal cord injury trial update, blood stem cells in lungs, and using parsley for stem cell therapies

Taking Steps Toward Personalized Heart Transplants

Over five million Americans have heart failure (HF), a condition in which the heart muscles become too weak to pump an adequate amount of blood, oxygen and nutrients to the body’s other organs. People with heart failure suffer from shortness of breath, chronic weakness and a fifty percent chance of dying within the first five … Continue reading Taking Steps Toward Personalized Heart Transplants

Growing Stem Cell Research in California (Video)

How a Gladstone scientist is using bioengineering to push the pace of stem cell research At CIRM, we strive to fund the most promising stem cell research and speed the advancement of stem cell treatments to patients who need them. Because we are a state agency, we generally focus on funding scientists, universities, and companies … Continue reading Growing Stem Cell Research in California (Video)

Scientists use cotton candy to make artificial blood vessels

Cotton candy gets a bad rap. The irresistible, brightly colored cloud of sugar is notorious for sending kids into hyperactive overdrive and wreaking havoc on teeth. While it’s most typically found at a state fair or at a sports stadium, cotton candy is now popping up at the lab bench and is re-branding itself into … Continue reading Scientists use cotton candy to make artificial blood vessels

CIRM Scholar Jessica Gluck on using stem cells to make biological pacemakers for the heart

As part of our CIRM scholar series, we feature the research accomplishments of students and postdocs that have received CIRM funding. I’d like to introduce you to one of our CIRM Scholars, Jessica Gluck. She’s currently a Postdoctoral Fellow at UC Davis working on human stem cell models of heart development. Jessica began her education … Continue reading CIRM Scholar Jessica Gluck on using stem cells to make biological pacemakers for the heart