Lab-made retinas offer a new approach to battling vision loss

Age-related macular degeneration (AMD) is the leading cause of vision loss in the elderly. Now, new research using 3D organoid models of the eye has uncovered clues as to what happens in AMD, and how to stop it.  In AMD, a person loses their central vision because the light sensitive cells in the macula, a … Continue reading Lab-made retinas offer a new approach to battling vision loss

Stem cell-derived retinal patch continues to show promising results two years post-implantation

Earlier this year we wrote about the promising results of a phase 1 clinical trial aimed at replacing the deteriorating cells in the retinas of people suffering from age-related macular degeneration- one of the leading causes of blindness worldwide for people over 50. Now there’s even more good news! Highlighted in a news story on … Continue reading Stem cell-derived retinal patch continues to show promising results two years post-implantation

How a tiny patch is helping restore lasting vision

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Researchers are working on a stem cell-based retinal implant that could be used for people with with advanced dry age-related macular degeneration. (Photo/ Britney O. Pennington) When Anna Kuehl began losing her vision, she feared losing the ability to read and go on long walks in … Continue reading How a tiny patch is helping restore lasting vision

Sometimes a cold stare is a good thing

A retina of a patient with macular degeneration. (Photo credit: Paul Parker/SPL) Age-related macular degeneration (AMD) is the leading cause of vision loss and blindness in the elderly in the U.S. It’s estimated that some 11 million Americans could have some form of the disease, a number that is growing every year. So if you … Continue reading Sometimes a cold stare is a good thing

CIRM-funded research aims to create a platform to test therapies for AMD

People with late stage age-related macular degeneration lose their central vision. So an image like the one on the left might appear to them as shown on the right. Credit: University of California - Santa Barbara Our vision is one of the most important senses that we use in our everyday lives. Whether its to … Continue reading CIRM-funded research aims to create a platform to test therapies for AMD

CIRM Board Approves $19.7 Million in Awards for Translational Research Program

In addition to approving funding for breast cancer related brain metastases last week, the CIRM Board also approved an additional $19.7 million geared towards our translational research program. The goal of this program is to help promising projects complete the testing needed to begin talking to the US Food and Drug Administration (FDA) about holding … Continue reading CIRM Board Approves $19.7 Million in Awards for Translational Research Program

CIRM-funded study helps unlock some of the genetic secrets behind macular degeneration

Retina affected by age-related macular degeneration Age-related macular degeneration (AMD) is the leading cause of vision loss in people over 60. It affects 10 million Americans. That’s more than cataracts and glaucoma combined. The causes of AMD are not known but are believed to involve a mixture of hereditary and environmental factors. There is no … Continue reading CIRM-funded study helps unlock some of the genetic secrets behind macular degeneration

The most popular Stem Cellar posts of 2018

You never know when you write something if people are going to read it. Sometimes you wonder if anyone is going to read it. So, it’s always fun, and educational, to look back at the end of the year and see which pieces got the most eyeballs. It isn’t always the ones you think will … Continue reading The most popular Stem Cellar posts of 2018

Stem Cell Agency’s Diane Winokur hailed as Visionary

Generally speaking, I am not a huge fan of gala dinners. It’s not that I don’t like seeing people who do remarkable things getting a well-deserved honor. It’s just that the dinners often go on too long and the food is usually not very good (hey, this is San Francisco, those things matter). But last … Continue reading Stem Cell Agency’s Diane Winokur hailed as Visionary

The moment of truth. A video about the stem cell therapy that could help millions of people going blind.

“No matter how much one prepares, the first patient is always something very special.” That’s how Dr. Mark Humayun describes his feelings as he prepared to deliver a CIRM-funded stem cell therapy to help someone going blind from dry age-related macular degeneration (AMD). Humayun, an ophthalmologist and stem cell researcher at USC, spent years developing … Continue reading The moment of truth. A video about the stem cell therapy that could help millions of people going blind.