Sickle shaped red blood cells The University of California, San Francisco (UCSF), in collaboration with UC Berkeley (UCB) and UC Los Angeles (UCLA), have been given permission by the US Food and Drug Administration (FDA) to launch a first-in-human clinical trial using CRISPR technology as a gene-editing technique to cure Sickle Cell Disease. This research … Continue reading Three UC’s Join Forces to Launch CRISPR Clinical Trial Targeting Sickle Cell Disease
UC Los Angeles
CIRM funding helps identify potential COVID-19 treatment
The steps of the virus growth cycle that can be targeted with therapies: The virus enters a host cell (1), the virus's genetic instructions are released, taking over cellular machinery (2), the virus is replicated within the cell (3) and copies of the virus exit the cell in search of new host cells to infect … Continue reading CIRM funding helps identify potential COVID-19 treatment
Charting a course for the future
A new home for stem cell research? Have you ever been at a party where someone says “hey, I’ve got a good idea” and then before you know it everyone in the room is adding to it with ideas and suggestions of their own and suddenly you find yourself with 27 pages of notes, all … Continue reading Charting a course for the future
Unlocking a key behind why our bones get weaker as we age
Magnified image of a bone with osteoporosis. Photo Courtesy Sciencephoto.com Getting older brings with it a mixed bag of items. If you are lucky you can get wiser. If you are not so lucky you can get osteoporosis. But while scientists don’t know how to make you wiser, they have gained some new insights into … Continue reading Unlocking a key behind why our bones get weaker as we age
CIRM funded researchers discover link between Alzheimer’s gene and COVID-19
Dr. Yanhong Shi (left) and Dr. Vaithilingaraja Arumugaswami (right) All this month we are using our blog and social media to highlight a new chapter in CIRM’s life, thanks to the voters approving Proposition 14. We are looking back at what we have done since we were created in 2004, and also looking forward to the … Continue reading CIRM funded researchers discover link between Alzheimer’s gene and COVID-19
Progress in the fight against Sickle Cell Disease
Marissa Cors, sickle cell disease patient advocate Last November Marissa Cors, a patient advocate in the fight against Sickle Cell Disease (SCD), told the Stem Cellar “A stem cell cure will end generations of guilt, suffering, pain and early death. It will give SCD families relief from the financial, emotional and spiritual burden of caring … Continue reading Progress in the fight against Sickle Cell Disease
Anticipating the Future of Regenerative Medicine: CIRM’s Alpha Stem Cell Clinics Network
All this month we are using our blog and social media to highlight a new chapter in CIRM’s life, thanks to the voters approving Proposition 14. We are looking back at what we have done since we were created in 2004, and also looking forward to the future. Today we take a deeper dive into … Continue reading Anticipating the Future of Regenerative Medicine: CIRM’s Alpha Stem Cell Clinics Network
Inspiring new documentary about stem cell research
Poster for the documentary "Ending Disease" 2020 has been, to say the very least, a difficult and challenging year for all of us. But while the focus of the world has, understandably, been on the coronavirus there was also some really promising advances in stem cell research. Those advances are captured in a great new … Continue reading Inspiring new documentary about stem cell research
UCLA scientists discover how SARS-CoV-2 causes multiple organ failure in mice
Heart muscle cells in an uninfected mouse (left) and a mouse infected with SARS-CoV-2 (right) with mitochondria seen in pink. The disorganization of the cells and mitochondria in the image at right is associated with irregular heartbeat and death. Image credit: UCLA Broad Stem Cell Center As the worldwide coronavirus pandemic rages on, scientists are trying … Continue reading UCLA scientists discover how SARS-CoV-2 causes multiple organ failure in mice
CIRM funded trial for sickle cell disease gives patient a chance for a better future
Evie Junior is participating in a CIRM funded clinical trial for sickle cell disease that uses a stem cell gene therapy approach. Image credit: UCLA Broad Stem Cell Research Center For Evie Junior, personal health and fitness have always been a top priority. During his childhood, he was active and played football, basketball, and baseball … Continue reading CIRM funded trial for sickle cell disease gives patient a chance for a better future
The Stem Cellar 