Dr. Thomas Rando, Stanford University While we're all at home and practicing social distancing during this global pandemic, it has become a challenge to get in daily exercise. Aside from outward physical appearance, what other benefits does exercise hold? Dr. Thomas Rando and his team at Stanford University explored this question in more detail in … Continue reading Study shows that exercise rejuvenates muscle stem cells of old mice
Stanford University
Big time validation for early support
It’s not every day that a company and a concept that you helped support from the very beginning gets snapped up for $4.9 billion. But that’s what is happening with Forty Seven Inc. and their anti-cancer therapies. Gilead, another California company by the way, has announced it is buying Forty Seven Inc. for almost $5 … Continue reading Big time validation for early support
Donor blood stem cells and T cells could help patients wean off immunosuppressive drugs after organ transplant
Dr. Samuel Strober is refining a process that eliminates the need for the many immunosuppresant drugs normally required after a transplant.Image credit: Stanford Medicine News Center In 2019, there were over 23,000 kidney transplants in the United States, according to figures from the United Network for Organ Sharing (UNOS). These transplants can be lifesaving, but … Continue reading Donor blood stem cells and T cells could help patients wean off immunosuppressive drugs after organ transplant
Dashed Dreams and New Hope: A Quest to Cure Thymic Deficiency
By Kelly Shepard, PhD., CIRM's Associate Director, Discovery & Translation CIRM has previously blogged about advances in treating certain forms of “bubble baby” disease”, where a person is born with a defect in their blood forming stem cells that results in a deficient immune system, rendering them vulnerable to lethal infections by all manner of … Continue reading Dashed Dreams and New Hope: A Quest to Cure Thymic Deficiency
Facebook Live: Ask the Stem Cell Team
On December 12th we hosted our latest 'Facebook Live: Ask the Stem Cell Team' event. This time around we really did mean team. We had a host of our Science Officers answering questions from friends and supporters of CIRM. We got a lot of questions and didn't have enough time to address them all. So … Continue reading Facebook Live: Ask the Stem Cell Team
Two CIRM supported studies highlighted in Nature as promising approaches for blood disorders
Blood stem cells (blue) are cleared from the bone marrow (purple) before new stem cells can be transplanted.Credit: Dennis Kunkel Microscopy/SPL Problems with blood stem cells, a type of stem cell in your bone marrow that gives rise to various kinds of blood cells, can sometimes result in blood cancer as well as genetic and … Continue reading Two CIRM supported studies highlighted in Nature as promising approaches for blood disorders
What is IPEX syndrome? A deeper dive into a CIRM funded award
Brian Lookofsky (left) and his son Taylor Lookofsky (right) at the CIRM Board meeting on October 31, 2019. Taylor is living with IPEX syndrome. Last week we shared a powerful story of patient advocate Taylor Lookofsky, a young man with IPEX syndrome. In his speech, he talked about the impact the condition has had on … Continue reading What is IPEX syndrome? A deeper dive into a CIRM funded award
Transplanted stem cells used to grow fully functional lungs in mice
Illustration of a human lung According to organ donation statistics from the Health Resources & Services Administration, over 113,000 men, women, and children are on the national transplant waiting list as of July 2019. Another person is added to the waiting list every 10 minutes and 20 people die each day waiting for a transplant. … Continue reading Transplanted stem cells used to grow fully functional lungs in mice
The challenges of living with IPEX
Last week the CIRM Board awarded $5.53 million to Dr. Rosa Bacchetta at Stanford to complete the work necessary to conduct a clinical trial for IPEX syndrome. This is a rare disease caused by mutations in the FOXP3 gene which leaves people with the condition vulnerable to immune system attacks on their organs and tissues. … Continue reading The challenges of living with IPEX
Stem Cell Agency Approves Funding for Clinical Trials Targeting Parkinson’s Disease and Blindness
The governing Board of the California Institute for Regenerative Medicine (CIRM) yesterday invested $32.92 million to fund the Stem Cell Agency’s first clinical trial in Parkinson’s disease (PD), and to support three clinical trials targeting different forms of vision loss. This brings the total number of clinical trials funded by CIRM to 60. The PD … Continue reading Stem Cell Agency Approves Funding for Clinical Trials Targeting Parkinson’s Disease and Blindness
The Stem Cellar 