Mending Stem Cells: The Past, Present & Future of Regenerative Medicine

UCSF's Mission Bay Campus For years we have talked about the “promise” and the “potential” of stem cells to cure patients. But more and more we are seeing firsthand how stem cells can change a patient’s life, even saving it in some cases. That’s the theme of the 4th Annual CIRM Alpha Stem Cell Clinics … Continue reading Mending Stem Cells: The Past, Present & Future of Regenerative Medicine

Promising start to CIRM-funded trial for life-threatening blood disorder

Aristotle At CIRM we are always happy to highlight success stories, particularly when they involve research we are funding. But we are also mindful of the need not to overstate a finding. To quote the Greek philosopher Aristotle (who doesn’t often make an appearance on this blog), “one swallow does not a summer make”. In … Continue reading Promising start to CIRM-funded trial for life-threatening blood disorder

New model unlocks clues to treating deadly childhood cancer

CIRM-funded research at Sanford Burnham Prebys Medical Discovery Institute in San Diego is identifying compounds that could be used to help children battling a deadly brain cancer. The cancer is choroid plexus carcinoma (CPC), a rare brain tumor that occurs mainly in children. As it grows the tumor can affect nearby parts of the brain … Continue reading New model unlocks clues to treating deadly childhood cancer

Rats, research and the road to new therapies

Don Reed Don Reed has been a champion of CIRM even before there was a CIRM. He's a pioneer in pushing for funding for stem cell research and now he's working hard to raise awareness about the difference that funding is making. In a recent article on Daily Kos, Don highlighted one of the less … Continue reading Rats, research and the road to new therapies

Gene therapy gives patient a cure and a new lease on life

Brenden Whittaker (left), of Ohio, is a patient born with a rare genetic immune disease who was treated at the Dana-Farber/Boston Children’s Cancer and Blood Disorders Center in a CIRM funded gene therapy trial. Dr. David Williams (on right) is Brenden's treating physician.Photo courtesy of Rose Lincoln - Harvard Staff Photographer Pursuing an education can … Continue reading Gene therapy gives patient a cure and a new lease on life

Antibody effective in cure for rare blood disorders

3D illustration of an antibody binding to a designated target. Illustration created by Audra Geras. A variety of diseases can be traced to a simple root cause: problems in the bone marrow. The bone marrow contains specialized stem cells known as hematopoietic stem cells (HSCs) that give rise to different types of blood cells. As … Continue reading Antibody effective in cure for rare blood disorders

Stories that caught our eye: National Geographic takes a deep dive into iPS cells; Japanese researchers start iPS cell clinical trial for spinal cord injury; and do high fat diets increase your risk of colorectal cancer

Can cell therapy beat the most difficult diseases? That’s the question posed in a headline in National Geographic. The answer; maybe, but it is going to take time and money. The article focuses on the use of iPS cells, the man-made equivalent of embryonic stem cells that can be turned into any kind of cell … Continue reading Stories that caught our eye: National Geographic takes a deep dive into iPS cells; Japanese researchers start iPS cell clinical trial for spinal cord injury; and do high fat diets increase your risk of colorectal cancer

CIRM Invests in Chemotherapy-Free Approach to Rare But Deadly Childhood Disease

David Vetter, boy diagnosed with SCID Imagine being told that your seemingly healthy newborn baby has a life-threatening disease. In a moment your whole world is turned upside down. That’s the reality for families with a child diagnosed with severe combined immunodeficiency (SCID). Children with SCID lack a functioning immune system so even a simple … Continue reading CIRM Invests in Chemotherapy-Free Approach to Rare But Deadly Childhood Disease

Tips on how to be a great Patient Advocate from three of the best Advocates around

No one sets out to be a Patient Advocate. It’s something that you become because of something that happens to you. Usually it’s because you, or  a loved one or a friend, becomes ill and you want to help find a treatment. Whatever the reason, it is the start of a journey that often throws … Continue reading Tips on how to be a great Patient Advocate from three of the best Advocates around

Rare Disease Gets Big Boost from California’s Stem Cell Agency

UC Irvine's Dr. Leslie Thompson and patient advocate Frances Saldana after the CIRM Board vote to approve funding for Huntington's disease If you were looking for a poster child for an unmet medical need Huntington’s disease (HD) would be high on the list. It’s a devastating disease that attacks the brain, steadily destroying the ability … Continue reading Rare Disease Gets Big Boost from California’s Stem Cell Agency