Our 2025 Annual Report, Looking Forward: Advancing California’s Scientific Vision, is here. This year’s report captures a future-focused mission that highlights progress, momentum, and long-term impact. It reflects California’s leadership in science, evokes hope and possibility, and embraces continual advancement in regenerative medicine. Inside the report, you'll find: Powerful Voices: Patients, families, and researchers share … Continue reading Explore how CIRM is advancing California’s scientific vision
News
Neurona Doses First Patient in CIRM-Funded Bilateral Epilepsy Cell Therapy Trial
Image Credit: Canva Stock Photo Neurona Therapeutics has reached a major milestone in the development of its stem cell approach to treating epilepsy. The company recently announced that the first patient has been dosed in a Phase 1/2 clinical trial evaluating NRTX-1001, a cell therapy for adults whose epilepsy affects both sides of the brain … Continue reading Neurona Doses First Patient in CIRM-Funded Bilateral Epilepsy Cell Therapy Trial
CIRM awards $2.8 million to develop a gene therapy for rare neuromuscular disorders
Credit: Shutterstock The California Institute for Regenerative Medicine (CIRM) announced in January $100 million in funding for a broad range of projects, including four to support clinical programs. One of these was a $2.8 million award to Patricio Sepulveda, PhD, MBA, CEO of Amplo Biotechnology, Inc. That grant will support the development of a gene … Continue reading CIRM awards $2.8 million to develop a gene therapy for rare neuromuscular disorders
Advancing Heart Health: CIRM Funds Tenaya Therapeutics’ Gene Therapy Trial for ARVC
Histology of human cardiac muscle under microscope. Credit: Shutterstock The California Institute for Regenerative Medicine (CIRM) recently announced funding a series of projects spanning the earliest stages of research through to clinical trials. One of those projects was an $8 million award to Matthew Pollman, MD, MS, Senior Vice President of Clinical Development at Tenaya … Continue reading Advancing Heart Health: CIRM Funds Tenaya Therapeutics’ Gene Therapy Trial for ARVC
Honoring Dr. John Zaia: A Legacy of Science, Leadership, and Kindness
Photo Courtesy: City of Hope The scientific community lost a true pioneer with the passing of John A. Zaia, MD, a visionary virologist, gene therapy trailblazer, and esteemed leader at City of Hope. Dr. Zaia dedicated over four decades to advancing regenerative medicine, leaving a profound impact on HIV research, pediatric diseases, stem cell transplantation, … Continue reading Honoring Dr. John Zaia: A Legacy of Science, Leadership, and Kindness
FDA Grants RMAT Designation to Luxa Biotechnology’s CIRM-funded Dry AMD Therapy
Credit: Shutterstock The FDA has granted Regenerative Medicine Advanced Therapy (RMAT) designation for a project focused on vision loss that was funded in part by the California Institute for Regenerative Medicine (CIRM). This designation is given to highly promising regenerative medicine therapies that treat serious or life-threatening diseases with the goal of accelerating the path … Continue reading FDA Grants RMAT Designation to Luxa Biotechnology’s CIRM-funded Dry AMD Therapy
The Stem Cellar’s Most Read Blogs of 2024
2024 was a significant year for the California Institute for Regenerative Medicine (CIRM). We reached many milestones, including celebrating our 20th anniversary and introducing our Strategic Allocation Framework (SAF) impact goals, all while continuing to fund innovative research and advancements in regenerative medicine.The Stem Cellar blog is where we share these stories and achievements, providing … Continue reading The Stem Cellar’s Most Read Blogs of 2024
A Step Forward in the Fight Against Advanced Kidney Cancer
Photo Courtesy: Allogene Therapeutics Metastatic renal cell carcinoma (RCC) is an advanced form of kidney cancer with few treatment options and a five-year survival rate of less than 17%. With funding support from CIRM, Allogene Therapeutics is developing ALLO-316, an allogeneic CAR-T cell therapy which targets CD70—a protein highly expressed on clear cell renal cell … Continue reading A Step Forward in the Fight Against Advanced Kidney Cancer
Two CIRM-funded research projects receive RMAT designation from FDA
The U.S. Food and Drug Administration (FDA) has granted Regenerative Medicine Advanced Therapy (RMAT) designation to two research projects funded by the California Institute for Regenerative Medicine (CIRM). RMAT is a fast-track designation that can help speed up the development, review, and potential approval of treatments for serious or life-threatening diseases. The first RMAT designation … Continue reading Two CIRM-funded research projects receive RMAT designation from FDA
CIRM Welcomes New Board Members
The California Institute for Regenerative Medicine (CIRM) is thrilled to welcome a distinguished group of new board members and alternates, each bringing a wealth of experience and leadership in healthcare, research, and innovation. Joyce A. Sackey, MD, FACP Dr. Sackey joins CIRM as an alternate for Linda Boxer. As the inaugural Chief Equity, Diversity, and … Continue reading CIRM Welcomes New Board Members
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