New gene therapy aims to restore function in early-onset Parkinson’s

Image source: Shutterstock Nearly one million people in the U.S. are living with Parkinson’s disease, which causes progressive symptoms including tremors, stiffness, and gait and balance issues. Although there are medications to treat symptoms, the disease has no cure.  To date, the California Institute for Regenerative Medicine (CIRM) has invested more than $109 million in … Continue reading New gene therapy aims to restore function in early-onset Parkinson’s

How CIRM is moving to raise awareness of Parkinson’s Disease

Crissy Field was filled with vibrant colors and massive energy for the 10th annual Moving Day San Francisco event on Saturday, May 4th.  Even with the rain and wind, community members showed up to demonstrate their commitment to "moving to end Parkinson's." Moving Day is an annual fundraising walk that unites people living with Parkinson’s Disease, their caregivers, and … Continue reading How CIRM is moving to raise awareness of Parkinson’s Disease

CIRM Funds Clinical Research for Individualized Stem Cell Treatment for Parkinson’s

Stock image of Parkinson's disease nerve cells. The California Institute for Regenerative Medicine (CIRM) has approved an $8 million award to Aspen Neuroscience to advance an investigational stem cell-derived dopaminergic neuron replacement therapy for Parkinson’s disease (PD). This individualized potential therapy is being explored in a first-in-human Phase 1/2a clinical trial for patients with moderate … Continue reading CIRM Funds Clinical Research for Individualized Stem Cell Treatment for Parkinson’s

#Take6ForPD: CIRM Board member David Higgins shares why Parkinson’s awareness matters

April is Parkinson’s Awareness Month and the California Institute for Regenerative Medicine (CIRM) is joining the campaign to #Take6ForPD—take 6 minutes to raise Parkinson’s awareness and highlight our commitment to funding research for the disease.  In addition to highlighting our commitment to funding research for Parkinson's Disease, we're also giving patients and patient advocates the opportunity to … Continue reading #Take6ForPD: CIRM Board member David Higgins shares why Parkinson’s awareness matters

CIRM commits $60 million for Parkinson’s research, joins #Take6ForPD awareness campaign 

April is Parkinson’s Awareness Month and the California Institute for Regenerative Medicine (CIRM) is joining the campaign to #Take6ForPD—take 6 minutes to raise Parkinson’s awareness and highlight our commitment to funding research for the disease.  What is Parkinson’s Disease?  Parkinson's disease (PD) is a neurodegenerative disease that affects nearly 1 million people in the United States … Continue reading CIRM commits $60 million for Parkinson’s research, joins #Take6ForPD awareness campaign 

California agency invests $4 million in stem cell treatment for Parkinson’s Disease

The California Institute for Regenerative Medicine (CIRM) is investing $4 million in a late-stage preclinical project by Ryne Bio aiming to improve treatment for Idiopathic Parkinson's disease (PD). PD is characterized by a loss of dopamine producing neurons that result in motor symptoms, such as dyskinesias (involuntary, erratic, writhing movements of the face, arms, legs … Continue reading California agency invests $4 million in stem cell treatment for Parkinson’s Disease

Stem Cell Agency Board Invests in 19 Discovery Research Programs Targeting Cancers, Heart Disease and Other Disorders

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Dr. Judy Shizuru, Stanford University While stem cell and gene therapy research has advanced dramatically in recent years, there are still many unknowns and many questions remaining about how best to use these approaches in developing therapies. That’s why the governing Board of the California Institute … Continue reading Stem Cell Agency Board Invests in 19 Discovery Research Programs Targeting Cancers, Heart Disease and Other Disorders

Replacement brain cells offer hope for Parkinson’s treatment

A colony of iPSCs from a Parkinson's patient (left) and dopaminergic neurons made from these iPSCs (right) to model PD. (Image credit: Jeanne Loring) A new study that used adult blood stem cells to create replacement brain nerve cells appears to help rats with Parkinson’s. In Parkinson’s, the disease attacks brain nerve cells that produce … Continue reading Replacement brain cells offer hope for Parkinson’s treatment

Stem cell treatment improves motor function in monkeys modeling Parkinson’s Disease

Neurodegenerative diseases impact millions of people worldwide with the risk of being affected by one of these diseases increasing as you get older. For many of these diseases, there are very few treatments available to patients. As life expectancy increases and the population continues to age, it is crucial to try and find treatments that … Continue reading Stem cell treatment improves motor function in monkeys modeling Parkinson’s Disease

Hollywood and Patient Advocacy – two people who are on our Board but never boring

At first glance, Lauren Miller Rogen and David Higgins, PhD, seem an unlikely pair. She’s an actor, writer, and director and has worked with some of the biggest names in Hollywood. He has a doctorate in molecular biology and genetics and has worked at some of the most well-known companies in biotech. But together they … Continue reading Hollywood and Patient Advocacy – two people who are on our Board but never boring