Retina affected by age-related macular degeneration Age-related macular degeneration (AMD) is the leading cause of vision loss in people over 60. It affects 10 million Americans. That’s more than cataracts and glaucoma combined. The causes of AMD are not known but are believed to involve a mixture of hereditary and environmental factors. There is no … Continue reading CIRM-funded study helps unlock some of the genetic secrets behind macular degeneration
Disease Areas
One year later, spinal cord therapy still looks promising
Jake Javier - participant in the SCIStar study The beginning of a clinical trial, particularly the first time a new therapy is being tested in people, is often a time of equal parts anticipation and nervousness. Anticipation, because you have been working to this point for many years. Nervousness, because you have never tested this … Continue reading One year later, spinal cord therapy still looks promising
CIRM Board Approves Funding for New Clinical Trials in Solid Tumors and Pediatric Disease
Dr. Theodore Nowicki, physician in the division of pediatric hematology/oncology at UCLA. Photo courtesy of Milo Mitchell/UCLA Jonsson Comprehensive Cancer Center The governing Board of the California Institute for Regenerative Medicine (CIRM) awarded two grants totaling $11.15 million to carry out two new clinical trials. These latest additions bring the total number of CIRM funded … Continue reading CIRM Board Approves Funding for New Clinical Trials in Solid Tumors and Pediatric Disease
Advancing stem cell research in many ways
Speakers at the Alpha Stem Cell Clinics Network Symposium: Photo by Marco Sanchez From Day One CIRM’s goal has been to advance stem cell research in California. We don’t do that just by funding the most promising research -though the 51 clinical trials we have funded to date clearly shows we do that rather well … Continue reading Advancing stem cell research in many ways
200 years later, the search for a cure for Parkinson’s continues
On the surface, actor Michael J. Fox, singer Neil Diamond, civil rights activist Jesse Jackson and Scottish comedian Billy Connolly would appear to have little in common. Except for one thing. They all have Parkinson’s Disease (PD). Their celebrity status has helped raise public awareness about the condition, but studies show that awareness doesn’t amount … Continue reading 200 years later, the search for a cure for Parkinson’s continues
First patient treated for colon cancer using reprogrammed adult cells
Dr. Sandip Patel (left) and Dr. Dan Kaufman (center) of UC San Diego School of Medicine enjoy a light-hearted moment before Derek Ruff (right) receives the first treatment for cancer using human-induced pluripotent stem cells (hiPSCs). Photo courtesy of UC San Diego Health. For patients battling cancer for the first time, it can be quite … Continue reading First patient treated for colon cancer using reprogrammed adult cells
Mending Stem Cells: The Past, Present & Future of Regenerative Medicine
UCSF's Mission Bay Campus For years we have talked about the “promise” and the “potential” of stem cells to cure patients. But more and more we are seeing firsthand how stem cells can change a patient’s life, even saving it in some cases. That’s the theme of the 4th Annual CIRM Alpha Stem Cell Clinics … Continue reading Mending Stem Cells: The Past, Present & Future of Regenerative Medicine
Promising start to CIRM-funded trial for life-threatening blood disorder
Aristotle At CIRM we are always happy to highlight success stories, particularly when they involve research we are funding. But we are also mindful of the need not to overstate a finding. To quote the Greek philosopher Aristotle (who doesn’t often make an appearance on this blog), “one swallow does not a summer make”. In … Continue reading Promising start to CIRM-funded trial for life-threatening blood disorder
New model unlocks clues to treating deadly childhood cancer
CIRM-funded research at Sanford Burnham Prebys Medical Discovery Institute in San Diego is identifying compounds that could be used to help children battling a deadly brain cancer. The cancer is choroid plexus carcinoma (CPC), a rare brain tumor that occurs mainly in children. As it grows the tumor can affect nearby parts of the brain … Continue reading New model unlocks clues to treating deadly childhood cancer
Organoids revolutionize approach to studying a variety of diseases
Organoids There are limitations to studying cells under a microscope. To understand some of the more complex processes, it is critical to see how these cells behave in an environment that is similar to conditions in the body. The production of organoids has revolutionized this approach. Organoids are three-dimensional structures derived from stem cells that … Continue reading Organoids revolutionize approach to studying a variety of diseases
The Stem Cellar 