Photo Courtesy: City of Hope The scientific community lost a true pioneer with the passing of John A. Zaia, MD, a visionary virologist, gene therapy trailblazer, and esteemed leader at City of Hope. Dr. Zaia dedicated over four decades to advancing regenerative medicine, leaving a profound impact on HIV research, pediatric diseases, stem cell transplantation, … Continue reading Honoring Dr. John Zaia: A Legacy of Science, Leadership, and Kindness
Disease Areas
FDA Grants RMAT Designation to Luxa Biotechnology’s CIRM-funded Dry AMD Therapy
Credit: Shutterstock The FDA has granted Regenerative Medicine Advanced Therapy (RMAT) designation for a project focused on vision loss that was funded in part by the California Institute for Regenerative Medicine (CIRM). This designation is given to highly promising regenerative medicine therapies that treat serious or life-threatening diseases with the goal of accelerating the path … Continue reading FDA Grants RMAT Designation to Luxa Biotechnology’s CIRM-funded Dry AMD Therapy
Discovery Research into the Link Between Air Pollution and Autism
Infographic, provided by Dr. Liption and team, showcasing the link between air pollution and autism spectrum disorder As outlined in Proposition 14, one of the goals of the California Institute for Regenerative Medicine (CIRM) is to help accelerate discoveries that enhance our understanding of central nervous system (CNS) disorders. As part of this goal, CIRM … Continue reading Discovery Research into the Link Between Air Pollution and Autism
Using Genetic Sequencing and AI to Identify and Treat Schizophrenia
Top left to right: Tomasz Nowakowski, PhD, and Nevan Krogan, PhD Bottom left to right: Aparna Bhaduri, PhD; Matt State, PhD; Alice Ting, PhD; Trey Ideker, PhD; Willow Coyote-Maestas, PhD As outlined in Proposition 14, one of the goals of the California Institute for Regenerative Medicine (CIRM) is to help accelerate discoveries that enhance our … Continue reading Using Genetic Sequencing and AI to Identify and Treat Schizophrenia
How Discovery Research is Unlocking the DNA Behind Psychiatric Disorders
From top left to right: Xin Jin, PhD; Joseph Ecker, PhD; Rusty Gage, PhD Bottom left to right: Eran Mukamel, PhD and Maria Carol Marchetto, PhD As outlined in Proposition 14, one of the goals of the California Institute for Regenerative Medicine (CIRM) is to help accelerate discoveries that enhance our understanding of central nervous … Continue reading How Discovery Research is Unlocking the DNA Behind Psychiatric Disorders
Exploring the Genetic Foundations of Autism and Gene Therapy Treatments
Principal investigator Alex Pollen, PhD, with his co-investigators and team of researchers. As outlined in Proposition 14, one of the goals of the California Institute for Regenerative Medicine (CIRM) is to help accelerate discoveries that enhance our understanding of central nervous system (CNS) disorders. As part of this goal, CIRM launched the Research using Multidisciplinary, … Continue reading Exploring the Genetic Foundations of Autism and Gene Therapy Treatments
CIRM Funds new UCSD VERGE Center to Better Understand Schizophrenia and Autism
From top left to right: Anne Bang, PhD; Carrie Bearden, PhD; Eugene Yeo, PhD; Jonathan Sebat, PhD Bottom left to right: Alysson Moutri, PhD; Lilia Iakoucheva, PhD; Sébastien Jacquemont; Trey Ideker, PhD This blog is part of a series highlighting our ReMIND program and the researchers it’s supporting. To explore all features in the series, … Continue reading CIRM Funds new UCSD VERGE Center to Better Understand Schizophrenia and Autism
World AIDS Day at the 3rd Annual Timothy Ray Brown Community Cure Symposium
Event recap written by guest writer Jacqueline Hantgan, CIRM Sr. Outreach Advisor for Outreach and Advocacy December is HIV/AIDS Awareness Month. To commemorate this important event, CIRM recently supported the 3rd Annual Timothy Ray Brown Community Cure Symposium which took place at the Palm Springs Art Museum on World AIDS Day−December 1, 2024. It was … Continue reading World AIDS Day at the 3rd Annual Timothy Ray Brown Community Cure Symposium
Gene Therapy Brings Hope to Families Affected by Rare Immune Disorder
Photo Courtesy of Andrea Fernandez de Soto Imagine a life where every time you step outside, everything in your environment poses a life-threatening risk. For children born with ADA-SCID (adenosine deaminase severe combined immunodeficiency), this is a reality. Their immune systems are so compromised that a common cold or a simple scrape on the knee … Continue reading Gene Therapy Brings Hope to Families Affected by Rare Immune Disorder
A Step Forward in the Fight Against Advanced Kidney Cancer
Photo Courtesy: Allogene Therapeutics Metastatic renal cell carcinoma (RCC) is an advanced form of kidney cancer with few treatment options and a five-year survival rate of less than 17%. With funding support from CIRM, Allogene Therapeutics is developing ALLO-316, an allogeneic CAR-T cell therapy which targets CD70—a protein highly expressed on clear cell renal cell … Continue reading A Step Forward in the Fight Against Advanced Kidney Cancer
The Stem Cellar 