World AIDS Day at the 3rd Annual Timothy Ray Brown Community Cure Symposium

Event recap written by guest writer Jacqueline Hantgan, CIRM Sr. Outreach Advisor for Outreach and Advocacy December is HIV/AIDS Awareness Month. To commemorate this important event, CIRM recently supported the 3rd Annual Timothy Ray Brown Community Cure Symposium which took place at the Palm Springs Art Museum on World AIDS Dayโˆ’December 1, 2024. It was … Continue reading World AIDS Day at the 3rd Annual Timothy Ray Brown Community Cure Symposium

Gene Therapy Brings Hope to Families Affected by Rare Immune Disorder

Photo Courtesy of Andrea Fernandez de Soto Imagine a life where every time you step outside, everything in your environment poses a life-threatening risk. For children born with ADA-SCID (adenosine deaminase severe combined immunodeficiency), this is a reality. Their immune systems are so compromised that a common cold or a simple scrape on the knee … Continue reading Gene Therapy Brings Hope to Families Affected by Rare Immune Disorder

A Step Forward in the Fight Against Advanced Kidney Cancer

Photo Courtesy: Allogene Therapeutics Metastatic renal cell carcinoma (RCC) is an advanced form of kidney cancer with few treatment options and a five-year survival rate of less than 17%. With funding support from CIRM, Allogene Therapeutics is developing ALLO-316, an allogeneic CAR-T cell therapy which targets CD70โ€”a protein highly expressed on clear cell renal cell … Continue reading A Step Forward in the Fight Against Advanced Kidney Cancer

Two CIRM-funded research projects receive RMAT designation from FDA

The U.S. Food and Drug Administration (FDA) has granted Regenerative Medicine Advanced Therapy (RMAT) designation to two research projects funded by the California Institute for Regenerative Medicine (CIRM). RMAT is a fast-track designation that can help speed up the development, review, and potential approval of treatments for serious or life-threatening diseases. The first RMAT designation … Continue reading Two CIRM-funded research projects receive RMAT designation from FDA

Remembering CIRM board member and ALS patient advocate Fred Fisher

CIRM would like to honor the contributions of Fred Fisher, MSW, LCSW, a dedicated member of our Independent Citizensโ€™ Oversight Committee (ICOC) governing board and an enthusiastic patient advocate. Fred passed away in September.   Fred joined the CIRM ICOC as the ALS patient advocate in June 2021 and held various roles during his tenure, including … Continue reading Remembering CIRM board member and ALS patient advocate Fred Fisher

UCLA researchers exploring ways to prevent heart failure after heart attacks

ENPP1 is expressed in the region of scarring after injury to the heart. Cardiac muscle shown in red and ENPP1 in green demonstrates expression of ENPP1 in the region of scar formation. | Credit: Arjun Deb Lab/UCLA At the California Institute for Regenerative Medicine (CIRM), we support groundbreaking cardiovascular research from Discovery to Clinical as … Continue reading UCLA researchers exploring ways to prevent heart failure after heart attacks

California advancing our understanding of Alzheimerโ€™s disease using stem cellsย 

Over 14,000 people in Fresno County are living with Alzheimer's, and itโ€™s estimated that more than 720,000 people are living with the brain disorder in California.   Thatโ€™s why the California Institute for Regenerative Medicine (CIRM)โ€”a state of California agency dedicated to funding regenerative medicine researchโ€”joined the Alzheimer's Association Walk to End Alzheimerโ€™s in Fresno/Madera to … Continue reading California advancing our understanding of Alzheimerโ€™s disease using stem cellsย 

Story of Hope: Elpida Therapeutics’ Pioneer Study on Rare Nerve Disease CMT4J

CIRM awarded Elpida Therapeutics a $3.9 million grant in December 2023 to support a pioneering preclinical study on Charcot Marie Tooth disease type 4J (CMT4J).

From Undergraduate to Hero: Solano Student’s Life-Saving Bone Marrow Match Begins with One Swab

SCC student and CIRM trainee Jose Solorio donated bone marrow to save an 11-year-old patient's life in New York. In a remarkable display of compassion and scientific collaboration, Solano Community College (SCC) student Jose Solorio, a scholar in the college's biomanufacturing bachelor's program, has become a real-life hero. Through Solanoโ€™s partnership with the National Marrow … Continue reading From Undergraduate to Hero: Solano Student’s Life-Saving Bone Marrow Match Begins with One Swab

CIRM awards $8 million to Support Groundbreaking Gene Therapy for AML and MDS

Image source: Canva  Around 20,000 Americans are affected by acute myeloid leukemia (AML) each year. AML is a type of cancer that originates in the bone marrow and rapidly enters the bloodstream. Additionally, many individuals are impacted by myelodysplastic syndromes (MDS), which are blood disorders that result in the improper formation or functioning of blood … Continue reading CIRM awards $8 million to Support Groundbreaking Gene Therapy for AML and MDS