Illustration courtesy of Oncternal Therapeutics I often joke that my job here at CIRM is to be the official translator for the stem cell agency. I have to translate complex science into everyday English that people without a science background – that includes me – can understand. Think I’m joking? Try making sense of this. … Continue reading CIRM-funded clinical trial shows encouraging results for patients with chronic lymphocytic leukemia & mantle cell lymphoma
Cancer
CIRM funded clinical trial shows promising results for patients with blood cancers
An illustration of a macrophage, a vital part of the immune system, engulfing and destroying a cancer cell. Antibody 5F9 blocks a "don't eat me" signal emitted from cancer cells. Courtesy of Forty Seven, Inc. Myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) are both types of blood cancers that can be difficult to treat. CIRM … Continue reading CIRM funded clinical trial shows promising results for patients with blood cancers
How a see-through fish could one day lead to substitutes for bone marrow transplants
Human blood stem cells For years researchers have struggled to create human blood stem cells in the lab. They have done it several times with animal models, but the human kind? Well, that’s proved a bit trickier. Now a CIRM-funded team at UC San Diego (UCSD) think they have cracked the code. And that would … Continue reading How a see-through fish could one day lead to substitutes for bone marrow transplants
Stories that caught our eye: FDA grants orphan drug status to CIRM-funded therapy; stunning discovery upends ideas of cell formation; and how tadpoles grow new tails
Gut busting discovery Intestinal stem cells: Photo courtesy Klaus Kaestner, Penn Institute for Regenerative Medicine It’s not often you read the word “sensational” in a news release about stem cells. But this week researchers at the University of Copenhagen released findings that are overturning long-held ideas about the development of cells in our stomachs. So … Continue reading Stories that caught our eye: FDA grants orphan drug status to CIRM-funded therapy; stunning discovery upends ideas of cell formation; and how tadpoles grow new tails
CIRM Board Approves Funding for New Clinical Trials in Solid Tumors and Pediatric Disease
Dr. Theodore Nowicki, physician in the division of pediatric hematology/oncology at UCLA. Photo courtesy of Milo Mitchell/UCLA Jonsson Comprehensive Cancer Center The governing Board of the California Institute for Regenerative Medicine (CIRM) awarded two grants totaling $11.15 million to carry out two new clinical trials. These latest additions bring the total number of CIRM funded … Continue reading CIRM Board Approves Funding for New Clinical Trials in Solid Tumors and Pediatric Disease
First patient treated for colon cancer using reprogrammed adult cells
Dr. Sandip Patel (left) and Dr. Dan Kaufman (center) of UC San Diego School of Medicine enjoy a light-hearted moment before Derek Ruff (right) receives the first treatment for cancer using human-induced pluripotent stem cells (hiPSCs). Photo courtesy of UC San Diego Health. For patients battling cancer for the first time, it can be quite … Continue reading First patient treated for colon cancer using reprogrammed adult cells
New model unlocks clues to treating deadly childhood cancer
CIRM-funded research at Sanford Burnham Prebys Medical Discovery Institute in San Diego is identifying compounds that could be used to help children battling a deadly brain cancer. The cancer is choroid plexus carcinoma (CPC), a rare brain tumor that occurs mainly in children. As it grows the tumor can affect nearby parts of the brain … Continue reading New model unlocks clues to treating deadly childhood cancer
Newly developed biosensor can target leukemic stem cells
Dr. Michael Milyavsky (left) and his research student Muhammad Yassin (right). Image courtesy of Tel Aviv University. Every three minutes, one person in the United States is diagnosed with a blood cancer, which amounts to over 175,000 people every year. Every nine minutes, one person in the United States dies from a blood cancer, which … Continue reading Newly developed biosensor can target leukemic stem cells
Facebook Live – Ask the Stem Cell Team about Patient Advocacy
How often do you get to ask an expert a question about something that matters deeply to you and get an answer right away? Not very often I'm guessing. That's why CIRM's Facebook Live "Ask the Stem Cell Team About Patient Advocacy" gives you a chance to do just that this Thursday, March 14th from … Continue reading Facebook Live – Ask the Stem Cell Team about Patient Advocacy
Antibody effective in cure for rare blood disorders
3D illustration of an antibody binding to a designated target. Illustration created by Audra Geras. A variety of diseases can be traced to a simple root cause: problems in the bone marrow. The bone marrow contains specialized stem cells known as hematopoietic stem cells (HSCs) that give rise to different types of blood cells. As … Continue reading Antibody effective in cure for rare blood disorders
The Stem Cellar 