Amyotrophic lateral sclerosis (ALS), better known as Lou Gehrig’s disease, was first identified way back in 1869 but today, more than 150 years later, there are still no effective treatments for it. Now a project, funded by CIRM, has been given approval by the Food and Drug Administration (FDA) to start a clinical trial that … Continue reading Ingenious CIRM-funded stem cell approach to treating ALS gets go-ahead to start clinical trial
Clinical Trials
Creating a “Pitching Machine” to speed up our delivery of stem cell treatments to patients
When baseball players are trying to improve their hitting they’ll use a pitching machine to help them fine tune their stroke. Having a device that delivers a ball at a consistent speed can help a batter be more consistent and effective in their swing, and hopefully get more hits. That’s what we are hoping our … Continue reading Creating a “Pitching Machine” to speed up our delivery of stem cell treatments to patients
Trash talking and creating a stem cell community
Imilce Rodriguez-Fernandez likes to talk trash. No, really, she does. In her case it’s cellular trash, the kind that builds up in our cells and has to be removed to ensure the cells don’t become sick. Imilce was one of several stem cell researchers who took part in a couple of public events over the … Continue reading Trash talking and creating a stem cell community
Using skin cells to repair damaged hearts
When someone has a heart attack, getting treatment quickly can mean the difference between life and death. Every minute delay in getting help means more heart cells die, and that can have profound consequences. One study found that heart attack patients who underwent surgery to re-open blocked arteries within 60 minutes of arriving in the … Continue reading Using skin cells to repair damaged hearts
Bioengineered veins give hope to kidney disease patients on dialysis
As blood travels around your body, it helps your body get around. Blood is essential for delivering oxygen and nutrients to all the cells in your body and for removing waste products made by these cells. Your body contains approximately 1.5 gallons of blood, which translates to around 7% of your body weight. In order … Continue reading Bioengineered veins give hope to kidney disease patients on dialysis
Ready, Set, Go: CIRM funded clinical trial for heart disease finishes patient enrollment
Heart disease is the leading cause of death in the United States with over 600,000 deaths occurring per year. Patients with heart disease or heart failure are given treatments that attempt to prevent their condition from getting worse or improve some of their symptoms. However, no treatment exists that can completely restore their heart function … Continue reading Ready, Set, Go: CIRM funded clinical trial for heart disease finishes patient enrollment
Stem Cell Experts Discuss the Ethical Implications of Translating iPSCs to the Clinic
Part of The Stem Cellar blog series on 10 years of iPSCs. This year, scientists are celebrating the 10-year anniversary of Shinya Yamanaka’s Nobel Prize winning discovery of induced pluripotent stem cells (iPSCs). These are cells that are very similar biologically to embryonic stem cells and can develop into any cell in the body. iPSCs … Continue reading Stem Cell Experts Discuss the Ethical Implications of Translating iPSCs to the Clinic
Full Steam Ahead: First Patient is Dosed in Expanded CIRM Spinal Cord Injury Trial
Today we bring you more good news about a CIRM-funded clinical trial for spinal cord injury that’s received a lot of attention lately in the news. Asterias Biotherapeutics has treated its first patient in an expanded patient population of spinal cord injury patients who suffer from cervical, or neck, injuries. In late August, Asterias reported … Continue reading Full Steam Ahead: First Patient is Dosed in Expanded CIRM Spinal Cord Injury Trial
Funding stem cell research targeting a rare and life-threatening disease in children
If you have never heard of cystinosis you should consider yourself fortunate. It’s a rare condition caused by an inherited genetic mutation. It hits early and it hits hard. Children with cystinosis are usually diagnosed before age 2 and are in end-stage kidney failure by the time they are 9. If that’s not bad enough … Continue reading Funding stem cell research targeting a rare and life-threatening disease in children
Asterias’ stem cell clinical trial shows encouraging results for spinal cord injury patients
When researchers are carrying out a clinical trial they have two goals: first, show that it is safe (the old “do no harm” maxim) and second, show it works. One without the other doesn’t do anyone any good in the long run. A few weeks ago Asterias Biotherapeutics showed that their CIRM-funded stem cell therapy … Continue reading Asterias’ stem cell clinical trial shows encouraging results for spinal cord injury patients
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