Gut busting discovery Intestinal stem cells: Photo courtesy Klaus Kaestner, Penn Institute for Regenerative Medicine It’s not often you read the word “sensational” in a news release about stem cells. But this week researchers at the University of Copenhagen released findings that are overturning long-held ideas about the development of cells in our stomachs. So … Continue reading Stories that caught our eye: FDA grants orphan drug status to CIRM-funded therapy; stunning discovery upends ideas of cell formation; and how tadpoles grow new tails
Clinical Trials
Stem cell model reveals deeper understanding into “ALS resilient” neurons
A descriptive illustration of Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's Disease. Courtesy of ALS Foundation website. Understanding the basic biology of how a cell functions can be crucial to being able to better understand a disease and unlock a potential approach for a treatment. Stem cells are unique in that they give … Continue reading Stem cell model reveals deeper understanding into “ALS resilient” neurons
CIRM-funded study helps unlock some of the genetic secrets behind macular degeneration
Retina affected by age-related macular degeneration Age-related macular degeneration (AMD) is the leading cause of vision loss in people over 60. It affects 10 million Americans. That’s more than cataracts and glaucoma combined. The causes of AMD are not known but are believed to involve a mixture of hereditary and environmental factors. There is no … Continue reading CIRM-funded study helps unlock some of the genetic secrets behind macular degeneration
The Past, the Present, and the Uncertain Future of Stem Cell Research
Ronnie, a boy who was born without a functioning immune system but who is thriving today because of CIRM funded research When CIRM was created in 2004 the field of stem cell research was still very much in its infancy. Fast forward 15 years and it’s moving ahead at a rapid pace, probably faster than … Continue reading The Past, the Present, and the Uncertain Future of Stem Cell Research
One year later, spinal cord therapy still looks promising
Jake Javier - participant in the SCIStar study The beginning of a clinical trial, particularly the first time a new therapy is being tested in people, is often a time of equal parts anticipation and nervousness. Anticipation, because you have been working to this point for many years. Nervousness, because you have never tested this … Continue reading One year later, spinal cord therapy still looks promising
CIRM Board Approves Funding for New Clinical Trials in Solid Tumors and Pediatric Disease
Dr. Theodore Nowicki, physician in the division of pediatric hematology/oncology at UCLA. Photo courtesy of Milo Mitchell/UCLA Jonsson Comprehensive Cancer Center The governing Board of the California Institute for Regenerative Medicine (CIRM) awarded two grants totaling $11.15 million to carry out two new clinical trials. These latest additions bring the total number of CIRM funded … Continue reading CIRM Board Approves Funding for New Clinical Trials in Solid Tumors and Pediatric Disease
Advancing stem cell research in many ways
Speakers at the Alpha Stem Cell Clinics Network Symposium: Photo by Marco Sanchez From Day One CIRM’s goal has been to advance stem cell research in California. We don’t do that just by funding the most promising research -though the 51 clinical trials we have funded to date clearly shows we do that rather well … Continue reading Advancing stem cell research in many ways
CIRM-funded therapy helps “bubble babies” lead a normal life
Ja'Ceon Golden; 'cured" of SCID At CIRM we are very cautious about using the “c” word. Saying someone has been “cured” is a powerful statement but one that loses its meaning when over used or used inappropriately. However, in the case of a new study from U.C. San Francisco and St. Jude Children’s Research Hospital … Continue reading CIRM-funded therapy helps “bubble babies” lead a normal life
Facebook Live: Ask the Stem Cell Team About Clinical Trials
Every day at CIRM we get emails and calls from people looking for a stem cell clinical trial to help them. Some have arthritis in the knee or hip and want to avoid surgery. Some have a child with autism and want something that will ease the symptoms. Some have cancer and conventional therapies no … Continue reading Facebook Live: Ask the Stem Cell Team About Clinical Trials
200 years later, the search for a cure for Parkinson’s continues
On the surface, actor Michael J. Fox, singer Neil Diamond, civil rights activist Jesse Jackson and Scottish comedian Billy Connolly would appear to have little in common. Except for one thing. They all have Parkinson’s Disease (PD). Their celebrity status has helped raise public awareness about the condition, but studies show that awareness doesn’t amount … Continue reading 200 years later, the search for a cure for Parkinson’s continues