Duchenne muscular dystrophy (DMD) is a particularly nasty rare and fatal disease. It predominantly affects boys, slowly robbing them of their ability to control their muscles. By 10 years of age, boys with DMD start to lose the ability to walk; by 12, most need a wheelchair to get around. Eventually they become paralyzed, and … Continue reading Stem cells could offer hope for deadly childhood muscle wasting disease
Adult Stem Cells
Gene editing in blood stem cells just got easier
Genome editing is a field of science that’s been around for awhile, but has experienced an explosion of activity and interest in recent years. Chances are that even your grandmother has heard about the recent story where for the first time, gene editing saved a one-year-old girl from dying of leukemia. Microsoft word versus genome … Continue reading Gene editing in blood stem cells just got easier
The key to unlocking stem cell’s potential and blocking a deadly threat
Our bodies are amazingly complex systems. By some estimates there are more than 37 trillion cells in our bodies. That’s trillion with a “t”. Each of those cells engages in some form of communication and signaling with other cells which makes our bodies one heck of a busy place to be. Yet all this activity … Continue reading The key to unlocking stem cell’s potential and blocking a deadly threat
Stem cell stories that caught our eye: cancer fighting virus, lab-grown guts work in dogs, stem cell trial to cure HIV
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Cancer fighting virus approved for melanoma (Disclaimer: While this isn’t a story about stem cells, it’s pretty cool so I had to include it.) The … Continue reading Stem cell stories that caught our eye: cancer fighting virus, lab-grown guts work in dogs, stem cell trial to cure HIV
Embryonic and man-made stem cells are almost identical
For years it has been the stem cell equivalent of the feud between the Hatfields and McCoys. The dispute centered on the question of which is better for advancing scientific research and developing new therapies, embryonic stem (ES) cells or induced pluripotent stem (iPS) cells? The somewhat surprising answer may be that they are both … Continue reading Embryonic and man-made stem cells are almost identical
How Brain Stem Cells Could Stay Forever Young
As we age, so do the cells that make up our bodies. To keep us spry as we get older, our bodies rely on adult stem cells to replace the cells in our tissues and organs. Adult stem cells can only generate cell types specific to the organ or tissue that they live in. For … Continue reading How Brain Stem Cells Could Stay Forever Young
Using satellites to build bigger biceps
There are several ways you can build bigger, stronger muscles. You can take the approach favored by our former Governor, Arnold Schwarzenegger, and pump iron till your biceps are as inflated as a birthday balloon. Or you could follow the lead of a research team we are funding and try to use stem cells to … Continue reading Using satellites to build bigger biceps
The Stem Cell Bank is open for business
When you go to a bank and withdraw money you know that the notes you get are all going to look the same and do the same job, namely allow you to buy things. But when you get stem cells for research that’s not necessarily the case. Stem cells bought from different laboratories don’t always … Continue reading The Stem Cell Bank is open for business
CIRM-funded clinical trial for spinal cord injury reports promising results
Today, the Menlo Park-based biotech company Asterias Biotherapeutics reported positive results from the first three patients treated in its Phase 1/2a clinical study using stem cell therapy to treat patients with spinal cord injury. This trial is funded by a CIRM Strategic Partnerships Award grant of $14.3 million. Asterias has developed a stem cell therapy … Continue reading CIRM-funded clinical trial for spinal cord injury reports promising results
Cell mate: the man who makes stem cells for clinical trials
When we announced that one of the researchers we fund - Dr. Henry Klassen at the University of California, Irvine - has begun his clinical trial to treat the vision-destroying disease retinitis pigmentosa, we celebrated the excitement felt by the researchers and the hope from people with the disease. But we missed out one group. … Continue reading Cell mate: the man who makes stem cells for clinical trials
The Stem Cellar 