Magnetic targeting technique has emerged as a new strategy to aid delivery, increase retention, and enhance the effects of mesenchymal stromal cells (MSCs) but, so far, has not been performed in lung diseases. With the aid of magnets, magnetized MSCs remained longer in the lungs, and this was associated with increased beneficial effects for the … Continue reading Magnetized stem cells used to treat lung disease in mice
California Institute for Regenerative Medicine
Super charging killer cells to fight leukemia
Colorized scanning electron micrograph of a natural killer cell.Photo credit: National Institute of Allergy and Infectious Diseases Racing car drivers are forever tinkering with their cars, trying to streamline them and soup up their engines because while fast is good, faster is better. Researchers do the same things with potential anti-cancer therapies, tinkering with them … Continue reading Super charging killer cells to fight leukemia
CIRM Board Approves Two Additional COVID-19 Projects
Dr. Vaithilingaraja Arumugaswami (left) and Dr. Song Li (right), UCLA Today the governing Board of the California Institute for Regenerative Medicine (CIRM) approved two additional projects as part of the $5 million in emergency funding for COVID-19 related projects. This brings the number of projects CIRM is supporting to 11, including two clinical trials. The Board awarded $349,999 … Continue reading CIRM Board Approves Two Additional COVID-19 Projects
Stem Cell Agency Board Approves Three More Projects Targeting COVID-19
Dr. Jianhua Yu (left), Dr. Helen Blau (center), and Dr. Albert Wong (right) The COVID-19 virus targets many different parts of the body, often with deadly or life-threatening consequences. This past Friday the governing Board of the California Institute for Regenerative Medicine (CIRM) approved investments in three early-stage research programs taking different approaches to battling … Continue reading Stem Cell Agency Board Approves Three More Projects Targeting COVID-19
Parkinson’s Disease and Stem Cells
Lila Collins, PhD A few weeks ago we held a Facebook Live "Ask the Stem Cell Team About Parkinson's Disease" event. As you can imagine we got lots of questions but, because of time constraints, only had time to answer a few. Thanks to my fabulous CIRM colleagues, Dr. Lila Collins and Dr. Kent Fitzgerald, … Continue reading Parkinson’s Disease and Stem Cells
CIRM Board Expands Efforts of COVID-19 Program
Today the governing Board of the California Institute for Regenerative Medicine (CIRM) expanded efforts related to the $5 million in emergency funding for the CIRM COVID-19 program. The new guidelines mean that inception discovery projects (DISC1), whose goal is developing new and transformational ideas, will now be eligible for CIRM COVID-19 funding. These projects can … Continue reading CIRM Board Expands Efforts of COVID-19 Program
A Tribute to Huntington’s Disease Warriors in the Age of COVID-19
Frances Saldana is one of the most remarkable women I know. She has lost all three of her children to Huntington's disease (HD) - a nasty, fatal disease that steadily destroys the nerve cells in the brain - but still retains a fighting spirit and a commitment to finding a cure for HD. She is … Continue reading A Tribute to Huntington’s Disease Warriors in the Age of COVID-19
Two rare diseases, two pieces of good news
Dr. Stephanie Cherqui Last week saw a flurry of really encouraging reports from projects that CIRM has supported. We blogged about two of them last Wednesday, but here’s another two programs showing promising results. UC San Diego researcher Dr. Stephanie Cherqui is running a CIRM-funded clinical trial for cystinosis. This is a condition where patients … Continue reading Two rare diseases, two pieces of good news
CIRM Board Approves Clinical Trials Targeting COVID-19 and Sickle Cell Disease
Coronavirus particles, illustration. Today the governing Board of the California Institute for Regenerative Medicine (CIRM) approved new clinical trials for COVID-19 and sickle cell disease (SCD) and two earlier stage projects to develop therapies for COVID-19. Dr. Michael Mathay, of the University of California at San Francisco, was awarded $750,000 for a clinical trial testing … Continue reading CIRM Board Approves Clinical Trials Targeting COVID-19 and Sickle Cell Disease
Promising results from CIRM-funded projects
Severe Leukocyte Adhesion Deficiency-1 (LAD-1) is a rare condition that causes the immune system to malfunction and reduces its ability to fight off viruses and bacteria. Over time the repeated infections can take a heavy toll on the body and dramatically shorten a person’s life. But now a therapy, developed by Rocket Pharmaceuticals, is showing … Continue reading Promising results from CIRM-funded projects
The Stem Cellar 