Dr. Mathew Blurton-Jones, leader of team that developed the chimeric "Mighty Mouse" model at the University of California, Irvine In ancient Greek mythology, a Chimera was a creature that was usually depicted as a lion with an additional goat head and a serpent for a tail. Due to the Chimera's animal hybrid nature, the term … Continue reading CIRM-Funded Researchers Develop Chimeric “Mighty Mouse” Model to Study Alzheimer’s Disease
Author: Yimy Villa
Newly discovered “don’t eat me” signal shows potential for ovarian and triple-negative breast cancer treatment
Stanford researchers have found that cancer cells have a protein called CD24 on their surface that enables them to protect themselves against the body's immune cells. Courtesy of Shutterstock Getting a breast cancer diagnosis is devastating news in and of itself. Currently, there are treatment options that target three different types of receptors, which are … Continue reading Newly discovered “don’t eat me” signal shows potential for ovarian and triple-negative breast cancer treatment
CIRM Board Approves $19.7 Million in Awards for Translational Research Program
In addition to approving funding for breast cancer related brain metastases last week, the CIRM Board also approved an additional $19.7 million geared towards our translational research program. The goal of this program is to help promising projects complete the testing needed to begin talking to the US Food and Drug Administration (FDA) about holding … Continue reading CIRM Board Approves $19.7 Million in Awards for Translational Research Program
CIRM Board Approves New Clinical Trial for Breast Cancer Related Brain Metastases
Dr. Saul Priceman Yesterday the governing Board of the California Institute for Regenerative Medicine (CIRM) awarded $9.28 million to Dr. Saul Priceman at City of Hope to conduct a clinical trial for the treatment of breast cancer related brain metastases, which are tumors in the brain that have spread from the original site of the … Continue reading CIRM Board Approves New Clinical Trial for Breast Cancer Related Brain Metastases
CIRM funded study identifies potential drug target for deadly heart condition
Joseph Wu is co-senior author of a study that demonstrates how patient-derived heart cells can help scientists better study the heart and screen potential therapies. Photo courtesy of Steve Fisch Heart disease continues to be the number one cause of death in the United States. An estimated 375,000 people have a genetic form of heart … Continue reading CIRM funded study identifies potential drug target for deadly heart condition
New study points to potential treatment for balance disorders
Alan Cheng and his colleagues were able to regenerate hair cells inside the ears of mice — a first in mature mammals. Photo Courtesy of Steve Fisch A sense of balance is important for a wide range of activities, from simple ones such as walking, running, and driving, to more intricate ones such as dancing, … Continue reading New study points to potential treatment for balance disorders
HIV eliminated from mice using CRISPR and LASER ART
Dr. Kamel Khalili In the United States alone, there are approximately 1.1 million people living with Human immunodeficiency virus (HIV), a virus that weakens the immune system by destroying important cells that fight off disease and infection. This number is much larger on a global scale, with 36.9 million people living with HIV as of … Continue reading HIV eliminated from mice using CRISPR and LASER ART
Regulated, reputable, and reliable – distinguishing legitimate clinical trials from predatory clinics
Here at CIRM, we get calls every day from patients asking us if there are any trials or therapies available to treat their illness or an illness affecting a loved one. Unfortunately, there are some predatory clinics that try to take advantage of this desperation by advertising unproven and unregulated treatments for a wide range … Continue reading Regulated, reputable, and reliable – distinguishing legitimate clinical trials from predatory clinics
Stories of the week – preterm birth and mice with a human immune system
While we are here at ISSCR 2019 hearing various scientists talk about their work, we realize that there are various breakthroughs in stem cell research in a wide variety of different fields going on every day. It is wonderful to see how scientists are hard at work in developing the latest science and pushing innovation. … Continue reading Stories of the week – preterm birth and mice with a human immune system
CIRM Board Approves New Clinical Trial for Rare Childhood Disease
Today the governing Board of the California Institute for Regenerative Medicine (CIRM) approved a grant of almost $12 million to Dr. Stephanie Cherqui at the University of California, San Diego (UCSD) to conduct a clinical trial for treatment of cystinosis. This award brings the total number of CIRM funded clinical trials to 55. Cystinosis is … Continue reading CIRM Board Approves New Clinical Trial for Rare Childhood Disease