Blood stem cells (blue) are cleared from the bone marrow (purple) before new stem cells can be transplanted.Credit: Dennis Kunkel Microscopy/SPL Problems with blood stem cells, a type of stem cell in your bone marrow that gives rise to various kinds of blood cells, can sometimes result in blood cancer as well as genetic and … Continue reading Two CIRM supported studies highlighted in Nature as promising approaches for blood disorders
Author: Yimy Villa
What to be thankful for this Thanksgiving: scientists hard at work
Biomedical technician Louis Pinedo feeds stem cells their special diet. Photo by Cedars-Sinai. With Thanksgiving and Black Friday approaching in the next couple of days, we wanted to give thanks to all the scientists hard at work during this holiday weekend. Science does not sleep--the groundbreaking research and experiments that are being conducted do not … Continue reading What to be thankful for this Thanksgiving: scientists hard at work
Machine learning used to pattern stem cells – a vital step in organ modeling
Gladstone researchers discovered a method to control the patterns stem cells form in a dish. The work was led by Senior Investigator Todd McDevitt (left) and his team, including (pictured) David Joy and Ashley Libby. When someone thinks of machine learning, the first thing that comes to mind might be the technology used by Netflix … Continue reading Machine learning used to pattern stem cells – a vital step in organ modeling
What is IPEX syndrome? A deeper dive into a CIRM funded award
Brian Lookofsky (left) and his son Taylor Lookofsky (right) at the CIRM Board meeting on October 31, 2019. Taylor is living with IPEX syndrome. Last week we shared a powerful story of patient advocate Taylor Lookofsky, a young man with IPEX syndrome. In his speech, he talked about the impact the condition has had on … Continue reading What is IPEX syndrome? A deeper dive into a CIRM funded award
Transplanted stem cells used to grow fully functional lungs in mice
Illustration of a human lung According to organ donation statistics from the Health Resources & Services Administration, over 113,000 men, women, and children are on the national transplant waiting list as of July 2019. Another person is added to the waiting list every 10 minutes and 20 people die each day waiting for a transplant. … Continue reading Transplanted stem cells used to grow fully functional lungs in mice
CIRM Board Awards $15.8 Million to Four Translational Research Projects
Last week, the CIRM Board approved $32.92 million in awards directed towards four new clinical trials in vision related diseases and Parkinson's Disease. In addition to these awards, the Board also approved investing $15.80 million in four awards in the Translational Research program. The goal of this program is to help promising projects complete the … Continue reading CIRM Board Awards $15.8 Million to Four Translational Research Projects
Stem Cell Agency Approves Funding for Clinical Trials Targeting Parkinson’s Disease and Blindness
The governing Board of the California Institute for Regenerative Medicine (CIRM) yesterday invested $32.92 million to fund the Stem Cell Agency’s first clinical trial in Parkinson’s disease (PD), and to support three clinical trials targeting different forms of vision loss. This brings the total number of clinical trials funded by CIRM to 60. The PD … Continue reading Stem Cell Agency Approves Funding for Clinical Trials Targeting Parkinson’s Disease and Blindness
NIH collaboration aims to develop affordable gene therapies for sickle cell disease and HIV
Sickle cell disease (SCD) and HIV have a major burden on the health of impoverished communities all over the world. Of the 38 million people living with HIV all over the world, approximately 95% reside within developing countries, with 67% in sub-Saharan Africa, half of whom are living without any treatment. Fifteen million babies will … Continue reading NIH collaboration aims to develop affordable gene therapies for sickle cell disease and HIV
USC study shows how tumor cells in the bloodstream can target distant organs
Various types of cancer can become particularly aggressive and difficult to treat once they spread from their initial point of origin to other parts of the body. This unfortunate phenomenon, known as metastasis, can make treatment very challenging, decreasing the chance of survival for the patient. In order to better understand this process, a CIRM … Continue reading USC study shows how tumor cells in the bloodstream can target distant organs
UCLA Conducts CAR-T Cell Clinical Trial for Patients with Recurring and Non-Responsive Cancers
Dr. Sarah Larson (left) and Dr. Yvonne Chen (right) There have been many advances made towards the treatment of various cancers, such as deadly forms of leukemia and lymphoma, that were once considered a death sentence and thought to be incurable. Unfortunately, there are still people who do not respond to treatment or eventually relapse … Continue reading UCLA Conducts CAR-T Cell Clinical Trial for Patients with Recurring and Non-Responsive Cancers
The Stem Cellar 