Sergiu Pasca’s three-dimensional culture makes it possible to watch how three different brain-cell types – oligodendrocytes (green), neurons (magenta) and astrocytes (blue) – interact in a dish as they do in a developing human brain. Courtesy of the Pasca lab Neurological diseases are among the most daunting diagnoses for a patient to receive, because they … Continue reading A new stem cell derived tool for studying brain diseases
Author: Pallavi Penumetcha
CIRM-supported Type I Diabetes treatment enters clinical trials in Europe
ViaCyte, a company that CIRM has supported for many years, has announced international expansion of a clinical trial to test their therapeutic PEC-Direct product in patients with Type I Diabetes. The first European patient in Brussels was implanted with the PEC-Direct product candidate that, in animal models, is able to form functional beta cells. Patients … Continue reading CIRM-supported Type I Diabetes treatment enters clinical trials in Europe
Using 3D printer to develop treatment for spinal cord injury
Spinal cord injuries (SCIs) affect approximately 300,000 Americans, with about 18,000 new cases occurring per year. One of these patients, Jake Javier, who we have written about many times over the past several years, received ten million stem cells as part of a CIRM-funded clinical trial and a video about his first year at Cal … Continue reading Using 3D printer to develop treatment for spinal cord injury
Midwest universities are making important tools to advance stem cell research
Two Midwest universities are making headlines for their contributions to stem cell research. Both are developing important tools to advance this field of study, but in two unique ways. Scientists at the University of Michigan (UM), have compiled an impressive repository of disease-specific stem cell lines. Cell lines are crucial tools for scientists to study … Continue reading Midwest universities are making important tools to advance stem cell research
New hope for stem cell therapy in patients with leukemia
Of the many different kinds of cancer that affect humans, leukemia is the most common in young people. As with many types cancer, doctors mostly turn to chemotherapy to treat patients. Chemotherapy, however, comes with its own share of issues, primarily severe side effects and the constant threat of disease recurrence. Stem cell therapy treatment … Continue reading New hope for stem cell therapy in patients with leukemia
Japanese scientists implant first Parkinson’s patient with replacement neurons derived from stem cells
Currently, more than 10 million people worldwide live with Parkinson’s disease (PD). By 2020, in the US alone, people living with Parkinson’s are expected to outnumber the cases of multiple sclerosis, muscular dystrophy and Lou Gehrig’s disease combined. There is no cure for Parkinson’s and treatment options consist of medications that patients ultimately develop tolerance … Continue reading Japanese scientists implant first Parkinson’s patient with replacement neurons derived from stem cells
CIRM invests $1.3 million to study stem cells in metabolic liver disease
Metabolic liver disease, is an emerging public health concern in Western countries, but has largely been overshadowed by health issues such as cancer and diabetes. Chronic liver disease (of which metabolic liver disease is a significant contributor) however, is a significant public health concern, evidenced by its contribution to nearly 2 million deaths per year … Continue reading CIRM invests $1.3 million to study stem cells in metabolic liver disease
Mechanical forces are the key to speedy recovery after blood cancer treatment
Blood cancers, such as leukemia and lymphoma, are projected to be responsible for 10% of all new cancer diagnoses this year. These types of cancers are often treated by killing the patient’s bone marrow (the site of blood cell manufacturing), with a treatment called irradiation. While effective for ridding the body of cancerous cells, this … Continue reading Mechanical forces are the key to speedy recovery after blood cancer treatment
A 3-D model of heart tissue gives scientists a leg up in studying heart disease
Hank Gathers was a 23-year-old basketball player at Loyola Marymount University with numerous accolades to his name and a promising future in the sport. This all came to an end when he suddenly collapsed in the middle of one of his games and subsequently passed away. It was the beginning of numerous such sudden death … Continue reading A 3-D model of heart tissue gives scientists a leg up in studying heart disease
A cancer therapy developed at a CIRM Alpha Stem Cell Clinic tests its legs against breast cancer
A Phase 1 clinical trial co-sponsored by CIRM and Oncternal Therapeutics, has started treating patients at UC San Diego (UCSD). The goal of the trial is to test the safety and anti-tumor activity of the Oncternal-developed drug, cirmtuzumab, in treating breast cancer. Breast cancer is the second most common cancer to occur in women, regardless … Continue reading A cancer therapy developed at a CIRM Alpha Stem Cell Clinic tests its legs against breast cancer
The Stem Cellar 