Key stem cell gene controlled from afar, Canadian scientists discover

Embryonic stem cells can, by definition, mature into any cell type in the body. They are able to maintain this state of so-called pluripotency with the help of a gene called Sox2. And now, researchers at the University of Toronto (U of T) have discovered the unseen force that controls it. These findings, reported in … Continue reading Key stem cell gene controlled from afar, Canadian scientists discover

A time to kill, a time to heal: cells linked to aging also help heal wounds

Senescent cells, so called because of the role they play in the aging process, have acquired a bit of a bad reputation. Yet new research from the Buck Institute suggests that these cells may not be so bad after all. Reporting in today's issue of Developmental Cell, Buck Institute scientists have found that, while senescent … Continue reading A time to kill, a time to heal: cells linked to aging also help heal wounds

December ICOC Board Meeting to Begin Soon

The December ICOC Board Meeting begins this morning in Berkeley, CA. The complete agenda can be found here. Dude to inclement weather our Spotlight on Disease has been canceled. For those not able to attend, you are welcome to dial in: To join the event as an attendee ------------------------------------------------------- 1. Go to https://cirm.webex.com/mw0307l/mywebex/default.do?nomenu=true&siteurl=cirm&service=6&rnd=0.3004049356896069&main_url=https%3A%2F%2Fcirm.webex.com%2Fec0606l%2Feventcenter%2Fevent%2FeventAction.do%3FtheAction%3Dlandingfrommail%26confViewID%3D2023263422%26%26EMK%3D4832534b0000000206e16422b6688520d75b860933effb35ce2c41b56594ba5351fdb8c0a969dd92%26email%3Dacheung%2540cirm.ca.gov%26encryptTicket%3Daee20fe734ccdae68884f9fe07b3197e%26%26siteurl%3Dcirm 2. Click … Continue reading December ICOC Board Meeting to Begin Soon

Finding the Sweet Spot: shifting metabolism keeps stem cells in suspended animation

The future is bright for a stem cell: it has the potential to become almost anything. This potential is one of its two defining characteristics. The second is that it can create copies of itself over and over again. This second characteristic, known as the ability to self-renew, is of particular importance to researchers. After … Continue reading Finding the Sweet Spot: shifting metabolism keeps stem cells in suspended animation

Stem Cell Stories that Caught our Eye: Stem Cell Summit Roundup, Spinal Cords in a Dish and Stem Cell Tourism in the NFL

Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Success at the World Stem Cell Summit. This week some of the biggest names in regenerative medicine descended upon San Antonio, Texas for the annual … Continue reading Stem Cell Stories that Caught our Eye: Stem Cell Summit Roundup, Spinal Cords in a Dish and Stem Cell Tourism in the NFL

Searching for a Cure for HIV/AIDS: Stem Cells and World AIDS Day

It's been 26 years since the first World AIDS Day was held in 1988—and the progress that the international scientific community has made towards eradicating the disease has been unparalleled. But there is much more work to be done. One of the most promising areas of HIV/AIDS research has been in the field of regenerative … Continue reading Searching for a Cure for HIV/AIDS: Stem Cells and World AIDS Day

Speak Friend and Enter: How Cells Let the Right Travelers through their Doors

For decades, it’s been a molecular mystery that scientists were seemingly unable to solve: how do large molecules pass through the cell and into the nucleus, while others half their size remain stranded outside? But as reported in the latest issue of Nature Nanotechnology, researchers now believe they may have cracked the case. By shedding … Continue reading Speak Friend and Enter: How Cells Let the Right Travelers through their Doors

Shape-Shifting Cells Drive Bone Healing; Point to New Method of Correcting Bone Deformities

There’s a time to grow and a time to heal—and the cells that make up our bone and cartilage have impeccable timing. During childhood and adolescence, these cells work to grow the bones longer and stronger. Once we’ve reached adulthood, they shift focus to repair and healing. This is part of why children with bone … Continue reading Shape-Shifting Cells Drive Bone Healing; Point to New Method of Correcting Bone Deformities

10 Years/10 Therapies: 10 Years after its Founding CIRM will have 10 Therapies Approved for Clinical Trials

In 2004, when 59 percent of California voters approved the creation of CIRM, our state embarked on an unprecedented experiment: providing concentrated funding to a new, promising area of research. The goal: accelerate the process of getting therapies to patients, especially those with unmet medical needs. Having 10 potential treatments expected to be approved for … Continue reading 10 Years/10 Therapies: 10 Years after its Founding CIRM will have 10 Therapies Approved for Clinical Trials

Entrepreneurship and Education

Guest author Neil Littman is CIRM's Business Development Officer. CIRM works closely with UCSF on a number of initiatives, from providing funding to academic investigators to jointly hosting events such as the recent CIRM Showcase with J-Labs held at the Mission Bay campus. Beyond our joint initiatives, UCSF also provides many other valuable resources and … Continue reading Entrepreneurship and Education