CIRM-supported therapy for blood cancers gets FDA fast track

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST People often complain about how long it can take to turn a scientific discovery into an approved therapy for patients. And they’re right. It can take years, decades even. But for Immune-Onc Therapeutics the path to FDA approval may just have been shortened. Back in April … Continue reading CIRM-supported therapy for blood cancers gets FDA fast track

Stem Cell Agency Board Invests in Therapy Targeting Deadly Blood Cancers

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Hematologic malignancies are cancers that affect the blood, bone marrow and lymph nodes and include different forms of leukemia and lymphoma. Current treatments can be effective, but in those patients that do not respond, there are few treatment options. Today, the governing Board of the California … Continue reading Stem Cell Agency Board Invests in Therapy Targeting Deadly Blood Cancers

CIRM Board Approves Clinical Trials for Blood Cancer and Pediatric Brain Tumors

Today the governing Board of the California Institute for Regenerative Medicine (CIRM) awarded $14.4 million for two new clinical trials for blood cancer and pediatric brain tumors. These awards bring the total number of CIRM-funded clinical trials to 70.  $6.0 million was awarded to Immune-Onc Therapeutics to conduct a clinical trial for patients with acute … Continue reading CIRM Board Approves Clinical Trials for Blood Cancer and Pediatric Brain Tumors

A CIRM-funded therapy for a deadly blood cancer gets approval for Phase 3 clinical trial

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Oncternal Therapeutics, Inc. is celebrating an encouraging milestone at the start of the new year following a successful End-of-Phase 2 meeting with the FDA.  Specifically, the FDA agreed on key elements of the company’s potentially pivotal Phase 3 clinical trial of zilovertamab, which offers potential treatment advantages to patients suffering from relapsed or refractory mantle cell lymphoma (MCL). Zilovertamab (previously called cirmtuzumab because … Continue reading A CIRM-funded therapy for a deadly blood cancer gets approval for Phase 3 clinical trial

How a health tech company is using virtual reality to treat stem cell patients 

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Virtual reality may soon be used to treat cancer patients who are recovering from stem cell procedures.   Healthcare technology company Rocket VR Health—in partnership with Massachusetts General Hospital—is developing a virtual reality (VR) therapy that intends to enhance the quality of life of cancer patients who … Continue reading How a health tech company is using virtual reality to treat stem cell patients 

DNA therapeutic treats blood cancer in mice and begins human clinical trial

Multiple myeloma is the second most common blood cancer in the United States, with more than 32,000 new cases predicted in 2020.  Unfortunately, many patients with this type of blood cancer eventually develop resistance to multiple types of treatments.  This phenomenon is partially due to the fact that cancer stem cells, which have the ability … Continue reading DNA therapeutic treats blood cancer in mice and begins human clinical trial

CIRM-funded trial for blood cancer releases promising new data

A CIRM-funded trial conducted by Oncternal Therapeutics in collaboration with UC San Diego released an interim clinical data update for patients with mantle cell lymphoma (MCL), a type of blood cancer. The treatment being developed involves an antibody called cirmtuzumab (named after yours truly) being used with a cancer fighting drug called ibrutinib. The antibody … Continue reading CIRM-funded trial for blood cancer releases promising new data

Study shows that COVID-19 vaccine is safe and effective in people with cancer

As we have seen in the US and all around the world, SARS-CoV-2, the virus that causes COVID-19, can cause severe complications and even death in many patients. In the early days of the pandemic, CIRM authorized $5 million in emergency funding for projects targeting the virus. To date CIRM has funded 20 projects related … Continue reading Study shows that COVID-19 vaccine is safe and effective in people with cancer

UCLA-led team creates first comprehensive map of human blood stem cell development

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST California researchers from UCLA and colleagues have created a first-of-its-kind roadmap that traces each step in the development of blood stem cells in the human embryo, providing scientists with a blueprint for producing fully functional blood stem cells in the lab.  The research, published in the … Continue reading UCLA-led team creates first comprehensive map of human blood stem cell development