Stem cell therapy may help mend a broken heart

Blausen.com staff (2014). "Medical gallery of Blausen Medical 2014 Dilated cardiomyopathy (DCM), a condition where the muscles of the heart are weak and can lead to heart failure, is considered rare in children. However, because the symptoms are not always easy to recognize the condition can go unnoticed for many years, and in severe cases … Continue reading Stem cell therapy may help mend a broken heart

Feds hit predatory stem cell clinics with a one-two punch

Federal Trade Commission Stem cells have a number of amazing properties and tremendous potential to heal previously untreatable conditions. But they also have the potential to create a financial windfall for clinics that are more focused on lining their wallets than helping patients. Now the federal government is cracking down on some of these clinics … Continue reading Feds hit predatory stem cell clinics with a one-two punch

CIRM funds clinical trials targeting heart disease, stroke and childhood brain tumors

Gary Steinberg (Jonathan Sprague) Heart disease and stroke are two of the leading causes of death and disability and for people who have experienced either their treatment options are very limited. Current therapies focus on dealing with the immediate impact of the attack, but there is nothing to deal with the longer-term impact. The CIRM … Continue reading CIRM funds clinical trials targeting heart disease, stroke and childhood brain tumors

Building a better brain (model) in the lab

Leica Picture of a brain organoid: courtesy National Institute of Allergy and Infectious Diseases, NIH One of the biggest problems with trying to understand what is happening in a disease that affects the brain is that it’s really difficult to see what is going on inside someone’s head. People tend to object to you trying … Continue reading Building a better brain (model) in the lab

Celebrating a young life that almost wasn’t

Often on the Stem Cellar we feature CIRM-funded work that is helping advance the field, unlocking some of the secrets of stem cells and how best to use them to develop promising therapies. But every once in a while it’s good to remind ourselves that this work, while it may often seem slow, is already … Continue reading Celebrating a young life that almost wasn’t

Paving the way for a treatment for dementia

What happens in a stroke When someone has a stroke, the blood flow to the brain is blocked. This kills some nerve cells and injures others. The damaged nerve cells are unable to communicate with other cells, which often results in people having impaired speech or movement. While ischemic and hemorrhagic strokes affect large blood … Continue reading Paving the way for a treatment for dementia

City of Hope researchers discover potential therapy to treat brain tumors

Glioblastoma (GBM) is a common type of aggressive brain tumor that is found in adults.  Survival of this type of brain cancer is poor with just 40% survival in the first-year post diagnosis and 17% in the second year, according to the American Association of Neurological Surgeons.  This disease has taken the life of former … Continue reading City of Hope researchers discover potential therapy to treat brain tumors

Learning life lessons in the lab

Rohan Upadhyay, CIRM SPARK student 2021 One of the most amazing parts of an amazing job is getting to know the students who take part in CIRM’s SPARK (Summer Program to Accelerate Regenerative Medicine Knowledge) program. It’s an internship giving high school students, that reflect the diversity of California, a chance to work in a … Continue reading Learning life lessons in the lab

SPARKing the genius of the next generation of scientists

Dr. Kelly Shepard, SPARK program director After almost 18 months – and counting – that have put us all to the test, made us wear masks, work from home, limit contact with all but the closest of family and friends it’s a wonderful thing to be able to get a glimpse of the future and … Continue reading SPARKing the genius of the next generation of scientists

A conversation with Bob Klein about the past, present, and future of CIRM

Bob Klein Anyone who knows anything about CIRM knows about Bob Klein. He's the main author and driving force behind both Proposition 71 and Proposition 14, the voter-approved ballot initiatives that first created and then refunded CIRM. It's safe to say that without Bob, there'd be no CIRM. Recently, we had the great good fortune … Continue reading A conversation with Bob Klein about the past, present, and future of CIRM