Investing in a stem cell treatment for Hurler syndrome

The California Institute for Regenerative Medicine (CIRM) awarded $5,444,353 to Dr. Natalia Gomez-Ospina and her team at Stanford University for a late-stage preclinical program targeting Severe Mucopolysaccharidosis type 1, also known as Hurler syndrome. This is an inherited condition caused by a faulty gene. Children with Hurler syndrome lack an enzyme that the body needs to digest … Continue reading Investing in a stem cell treatment for Hurler syndrome

Making transplants easier for kids, and charting a new approach to fighting solid tumors.

Every year California performs around 100 kidney transplants in children but, on average, around 50 of these patients will have their body reject the transplant. These children then have to undergo regular dialysis while waiting for a new organ. Even the successful transplants require a lifetime of immunosuppression medications. These medications can prevent rejection but … Continue reading Making transplants easier for kids, and charting a new approach to fighting solid tumors.

Study could pave the way in reducing decline in muscle strength as people age 

A study by Stanford Medicine researchers in older mice may lead to treatments that help seniors regain muscle strength lost to aging. Muscle stem cells—which are activated in response to muscle injury to regenerate damaged muscle tissue—lose their potency with age. A study from the National Health and Nutrition Examination Survey showed that five percent … Continue reading Study could pave the way in reducing decline in muscle strength as people age 

Chemistry Nobel Prize winner Carolyn Bertozzi had a hand in early stem cell research

Carolyn Bertozzi. Image credit: Andrew Brodhead The 2022 Nobel Prize in Chemistry has been awarded to Carolyn R. Bertozzi of Stanford University, Morten Meldal of the University of Copenhagen, and K. Barry Sharpless of Scripps Research. The three scientists are recognized for their independent development and contributions to the field known as click chemistry and bioorthogonal … Continue reading Chemistry Nobel Prize winner Carolyn Bertozzi had a hand in early stem cell research

The researcher who is following her bliss, and tackling diseases of aging at the same time

Dr. Jill Helms, and associate! Photo courtesy Stanford University Jill Helms is not your average Stanford University faculty member. Yes, she is a professor in the Department of Surgery. Yes, she has published lots of scientific studies. Yes, she is a stem cell scientist (funded by CIRM). And yes, she is playing a leading role … Continue reading The researcher who is following her bliss, and tackling diseases of aging at the same time

Fighting for his life and the lives of other stroke survivors

Sean Entin, stroke survivor and founder of Stroke Hacker The word "miraculous" gets tossed around a lot in the world of medicine, mostly by people who have made an unexpected recovery from a deadly or life-threatening condition. In Sean Entin's case calling his recovery from an almost-fatal stroke could be called miraculous, but I think … Continue reading Fighting for his life and the lives of other stroke survivors

Smoking marijuana could be bad for your heart, but there is an unusual remedy

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Smoking medical marijuana: Photo courtesy Elsa Olofsson Millions of Americans use marijuana for medical reasons, such as reducing anxiety or helping ease the side effects of cancer therapy. Millions more turn to it for recreational reasons, saying it helps them relax. Now a new study says … Continue reading Smoking marijuana could be bad for your heart, but there is an unusual remedy

Stem Cell Agency Board Approves Funding for Rare Immune Disorder

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Taylor Lookofsky (center), a person with IPEX syndrome, with his father Brian and Dr. Rosa Bacchetta IPEX syndrome is a rare condition where the body can’t control or restrain an immune response, so the person’s immune cells attack their own healthy tissue. The syndrome mostly affects … Continue reading Stem Cell Agency Board Approves Funding for Rare Immune Disorder

How two California researchers are advancing world class science to develop real life solutions

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST In our recently launched 5-year Strategic Plan, the California Institute for Regenerative Medicine (CIRM) profiled two researchers who have leveraged CIRM funding to translate basic biological discoveries into potential real-world solutions for devastating diseases. Dr. Joseph Wu is director of the Stanford Cardiovascular Institute and the recipient … Continue reading How two California researchers are advancing world class science to develop real life solutions

Bridges Scholar Spotlight: Samira Alwahabi

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST For more than a decade, CIRM has funded a number of educational and research training programs to give students the opportunity to explore stem cell science. One such project, the Bridges to Stem Cell Research program, helps train future generation of scientists by preparing undergraduate and … Continue reading Bridges Scholar Spotlight: Samira Alwahabi