Getting older is a normal, at times existential, part of life. The outward changes are abundant and noticeable: thinning of the hair, greying of the hair, and added lines to the face. There are also changes that happen that are not so abundantly clear in terms of outward appearance: slowing of healing time for bone … Continue reading Old cells need not apply: how a stem cell’s age can impact potential treatments
Spinal Cord Injury
Organoids revolutionize approach to studying a variety of diseases
Organoids Microscopes limit how well we can study cells. To understand complex processes, we must observe cells in conditions that mimic the body. Organoids have transformed this research. Organoids and "mini-brains" Organoids are three‑dimensional structures grown from stem cells that mimic real organs. Recent studies have used this method to explore a wide range of … Continue reading Organoids revolutionize approach to studying a variety of diseases
Using 3D printer to develop treatment for spinal cord injury
Spinal cord injuries (SCIs) affect approximately 300,000 Americans, with about 18,000 new cases occurring per year. One of these patients, Jake Javier, who we have written about many times over the past several years, received ten million stem cells as part of a CIRM-funded clinical trial and a video about his first year at Cal … Continue reading Using 3D printer to develop treatment for spinal cord injury
71 for Proposition 71
Proposition 71 is the state ballot initiative that created California's Stem Cell Agency. This month, the Agency reached another milestone when the 71st clinical trial was initiated in the CIRM Alpha Stem Cell Clinics (ASCC) Network. The ASCC Network deploys specialized teams of doctors, nurses and laboratory technicians to conduct stem cell clinical trials at … Continue reading 71 for Proposition 71
Stem Cell Agency celebrates 50 clinical trials with patient #1
Yesterday the CIRM Board approved funding for our 50th clinical trial (you can read about that here) It was an historic moment for us and to celebrate we decided to go back in history and hear from the very first person to be treated in a CIRM-funded clinical trial. Rich Lajara was treated in the … Continue reading Stem Cell Agency celebrates 50 clinical trials with patient #1
Has Regenerative Medicine Come of Age?
For the past few years the Signals blog site - which offers an insiders’ perspectives on the world of regenerative medicine and stem cell research - has hosted what it calls a "Blog Carnival". This is an event where bloggers from across the stem cell field are invited to submit a piece based on a … Continue reading Has Regenerative Medicine Come of Age?
Stem cell treatment for spinal cord injury offers improved chance of independent life for patients
A spinal cord injury is devastating, changing a person’s life in a heartbeat. In the past there was little that doctors could do other than offer pain relief and physical therapy to try and regain as much muscle function as possible. That’s why the latest results from the CIRM-supported Asterias Biotherapeutics spinal cord injury trial … Continue reading Stem cell treatment for spinal cord injury offers improved chance of independent life for patients
Stem Cell Roundup: Jake Javier’s amazing spirit; TV report highlights clinic offering unproven stem cell therapies
In the Roundup we usually focus on studies that highlight advances in stem cell research but today we’re going to do something a little different. Instead of relying on print for our stories, we’re turning to video. We begin with a piece about Jake Javier. Regular readers of our blog will remember that Jake is … Continue reading Stem Cell Roundup: Jake Javier’s amazing spirit; TV report highlights clinic offering unproven stem cell therapies
Friday Roundup: A better kind of blood stem cell transplant; Encouraging news from spinal cord injury trial; Finding an “elusive” cell that could help diabetics
Cool Instagram image of the week: Chemo- and radiation-free blood stem cell transplant showing promise Bubble baby disease, also known as severe combined immunodeficiency (SCID), is an inherited disorder that leaves newborns without an effective immune system. Currently, the only approved treatment for SCID is a blood stem cell transplant, in which the patient’s defective … Continue reading Friday Roundup: A better kind of blood stem cell transplant; Encouraging news from spinal cord injury trial; Finding an “elusive” cell that could help diabetics
Scientists repair spinal cord injuries in monkeys using human stem cells
An exciting development for spinal cord injury research was published this week in the journal Nature Medicine. Scientists from the University of San Diego School of Medicine transplanted human neural progenitor cells (NPCs) into rhesus monkeys that had spinal cord injuries. These cells, which are capable of turning into other cells in the brain, survived … Continue reading Scientists repair spinal cord injuries in monkeys using human stem cells