THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Researchers use mRNA to introduce the gene editor CRISPR-Cas9 into human muscle stem cells. These cells fused into multinucleated myotubes following mRNA-mediated CRISPR-Cas9 gene editing. A myosin heavy chain is seen in green and the nuclei in blue. Photo: Spuler Lab A team of researchers from … Continue reading How mRNA and CRISPR-Cas9 could treat muscle atrophy
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Friends, Romans, countrymen, lend me your ears – we have a podcast for you.
It seems like everyone, including my dog Freddie, has a podcast these days. So now we do too. According to the Podcasthosting.org website there are some two million podcasts in the world. Make that two million and one. That’s because CIRM is launching its own podcast and doing it with one of the biggest names … Continue reading Friends, Romans, countrymen, lend me your ears – we have a podcast for you.
How a CIRM scholar helped create a life-saving COVID vaccine
Dr. Derrick Rossi might be the most famous man whose name you don’t recognize. Dr. Rossi is the co-founder of Moderna. Yes, that Moderna. The COVID-19 vaccine Moderna. The vaccine that in clinical trials proved to be around 95 percent effective against the coronavirus. Dr. Rossi also has another claim to fame. He is a … Continue reading How a CIRM scholar helped create a life-saving COVID vaccine
Scientists develop faster, smarter way to classify tumors using single-cell technology
Dr. Stephen Lin, CIRM Senior Science Officer By Dr. Stephen Lin Single-cell. It is the new buzzword in biology. Single-cell biology refers to the in-depth characterization of individual cells in an organ or similar microenvironment. Every organ, like the brain or heart, is composed of thousands to millions of cells. Single-cell biology breaks those organs … Continue reading Scientists develop faster, smarter way to classify tumors using single-cell technology
Lab-grown human sperm cells could unlock treatments for infertility
Dr. Miles Wilkinson: Photo courtesy UCSD Out of 100 couples in the US, around 12 or 13 will have trouble starting a family. In one third of those cases the problem is male infertility (one third is female infertility and the other third is a combination of factors). In the past treatment options for men … Continue reading Lab-grown human sperm cells could unlock treatments for infertility
CIRM Board Approves Two Discovery Research Projects for COVID-19
Dr. Steven Dowdy (left), Dr. Evan Snyder (center), and Dr. John Zaia (right) This past Friday the governing Board of the California Institute for Regenerative Medicine (CIRM) approved two additional discovery research projects as part of the $5 million in emergency funding for COVID-19 related projects. This brings the number of COVID-19 projects CIRM is supporting to … Continue reading CIRM Board Approves Two Discovery Research Projects for COVID-19
How stem cells know the right way to make a heart . And what goes wrong when they don’t
Gladstone scientists Deepak Srivastava (left), Yvanka De Soysa (center), and Casey Gifford (right) publish a complete catalog of the cells involved in heart development. The invention of GPS navigation systems has made finding your way around so much easier, providing simple instructions on how to get from point A to point B. Now, a new … Continue reading How stem cells know the right way to make a heart . And what goes wrong when they don’t
Sequencing data points to genes involved in heart cell development
Australian scientists understand the genes involved in heart development used sequencing data to help pinpoint genes invovled in heart cell development. The findings of the study are published in the journal Cell Stem Cell. Dr. Nathan Palapant, of the Institute for Molecular Bioscience at the University of Queensland said offers insights for treating heart diseaes. … Continue reading Sequencing data points to genes involved in heart cell development
New findings about muscle stem cells reveals the potential for growing replacement organs
Chrissa Kioussi’s group at Oregon State University has made exciting advances in further unraveling the scientific mysteries of stem cells. In work detailed in Scientific Reports, this group found that muscle-specific stem cells actually have the ability to make multiple different cell types. Initially, this group was interested in understanding how gene expression changes during … Continue reading New findings about muscle stem cells reveals the potential for growing replacement organs
New target for defeating breast cancer stem cells uncovered
Stashed away in most of your tissues and organs lie small populations of adult stem cells. They help keep our bodies functioning properly by replenishing dying or damaged cells. Their ability to make more copies of themselves, as needed, ensures that there’s always an adequate supply set aside. But this very same self-renewing, life-sustaining property … Continue reading New target for defeating breast cancer stem cells uncovered