Blood stem cell transplant after high‑dose chemotherapy is standard care and can be curative for aggressive lymphoma. However, this approach often causes severe toxicity and life‑threatening complications due to delayed blood system recovery and vascular damage. Today, the CIRM Board funded a Phase 3 clinical trial to advance a safer, more tolerable alternative. CIRM Funding … Continue reading CIRM funds clinical trial for safer cancer therapy
lymphoma
Stem Cell Agency Board Invests in Therapy Targeting Deadly Blood Cancers
THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Dr. Ezra Cohen, photo courtesy UCSD Hematologic malignancies are cancers that affect the blood, bone marrow and lymph nodes and include different forms of leukemia and lymphoma. Current treatments can be effective, but in those patients that do not respond, there are few treatment options. Today, … Continue reading Stem Cell Agency Board Invests in Therapy Targeting Deadly Blood Cancers
A new approach to a deadly childhood cancer
THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Cancers of the blood, bone marrow and lymph nodes (also called hematologic malignancies) are the most common form of cancer in children and young adults. Current treatments can be effective but can also pose life-threatening health risks to the child. Now researchers at Stanford have developed … Continue reading A new approach to a deadly childhood cancer
Stem cell progress and promise in fighting leukemia
Computer illustration of a cancerous white blood cell in leukemia. There is nothing you can do to prevent or reduce your risk of leukemia. That’s not a very reassuring statement considering that this year alone almost 62,000 Americans will be diagnosed with leukemia; almost 23,000 will die from the disease. That’s why CIRM is funding … Continue reading Stem cell progress and promise in fighting leukemia
How a see-through fish could one day lead to substitutes for bone marrow transplants
Human blood stem cells For years researchers have struggled to create human blood stem cells in the lab. They have done it several times with animal models, but the human kind? Well, that’s proved a bit trickier. Now a CIRM-funded team at UC San Diego (UCSD) think they have cracked the code. And that would … Continue reading How a see-through fish could one day lead to substitutes for bone marrow transplants
Stem Cell Agency Board Approves 50th Clinical Trial
May 4th, 2011 marked a landmark moment for the California Institute for Regenerative Medicine (CIRM). On that day the Stem Cell Agency’s Board voted to invest in its first ever clinical trial, which was also the first clinical trial to use cells derived from embryonic stem cells. Today the Stem Cell Agency reached another landmark, … Continue reading Stem Cell Agency Board Approves 50th Clinical Trial
Mechanical forces are key to recovery after blood cancer treatment
Mesenchymal stem cells grown on a surface with specialized mechanical properties. Image courtesy of Krystyn Van Vliet at MIT. Blood cancers like leukemia and lymphoma will account for about 10% of all new cancer cases this year. Doctors often treat these diseases with irradiation, which kills the patient’s bone marrow — the source of blood … Continue reading Mechanical forces are key to recovery after blood cancer treatment
Stem Cell Agency Heads to Inland Empire for Free Patient Advocate Event
I am embarrassed to admit that I have never been to the Inland Empire in California, the area that extends from San Bernardino to Riverside counties. That’s about to change. On Monday, April 16th CIRM is taking a road trip to UC Riverside, and we’re inviting you to join us. We are holding a special, … Continue reading Stem Cell Agency Heads to Inland Empire for Free Patient Advocate Event
Surprise findings about bone marrow transplants could lead to more effective stem cell therapies
Some medical therapies have been around for so long that we naturally assume we understand how they work. That’s not always the case. Take aspirin for example. It’s been used for more than 4,000 years to treat pain and inflammation but it was only in the 1970’s that we really learned how it works. The … Continue reading Surprise findings about bone marrow transplants could lead to more effective stem cell therapies
Confusing cancer to kill it
Confusion is not a state of mind that we usually seek out. Being bewildered is bad enough when it happens naturally, so why would anyone actively pursue it? But now some researchers are doing just that, using confusion to not just block a deadly blood cancer, but to kill it. Today the CIRM Board approved … Continue reading Confusing cancer to kill it