Leukocyte Adhesion Deficiency-I (LAD-I) is a rare pediatric disease caused by a mutation in a specific gene that causes low levels of a protein called CD18. Due to low levels of CD18, the adhesion of immune cells is affected, which negatively impacts the body’s ability to combat infections. Rocket Pharmaceuticals has announced positive results from … Continue reading CIRM funded trial for LAD-I announces positive results
CIRM
CIRM Bridges program prepared student for research of a rare disease
Ian Blong, Ph.D., CIRM San Francisco State University Bridges to Stem Cell Research Alumnus Recently, The New York Times released a powerful article that tells the stories of four different families navigating the challenges of having a family member with a rare disease. One of these stories focused on Matt Wilsey, a tech entrepreneur and … Continue reading CIRM Bridges program prepared student for research of a rare disease
CIRM Funded Trial for Parkinson’s Treats First Patient
Dr. Krystof Bankiewicz Brain Neurotherapy Bio, Inc. (BNB) is pleased to announce the treatment of the first patient in its Parkinson’s gene therapy study. The CIRM-funded study, led by Dr. Krystof Bankiewicz, is one of the 64 clinical trials funded by the California state agency to date. Parkinson’s is a neurodegenerative movement disorder that affects … Continue reading CIRM Funded Trial for Parkinson’s Treats First Patient
CIRM-funded research aims to create a platform to test therapies for AMD
People with late stage age-related macular degeneration lose their central vision. So an image like the one on the left might appear to them as shown on the right. Credit: University of California - Santa Barbara Our vision is one of the most important senses that we use in our everyday lives. Whether its to … Continue reading CIRM-funded research aims to create a platform to test therapies for AMD
Driving Innovation While Addressing Health Disparities Among People of Color
Image courtesy of Science Photo Library One of the wonders of regenerative medicine is its broad applicability, which provides us with the opportunity to build upon existing knowledge and concepts. In the midst of a global pandemic, researchers have responded to the needs of patients severely afflicted with COVID-19 by repurposing existing therapies being developed … Continue reading Driving Innovation While Addressing Health Disparities Among People of Color
Therapy developed with CIRM award used in new clinical trial for COVID-19
Dr. Joshua Rhein, Assistant Professor of Medicine in the University of Minnesota Medical School's Division of Infectious Diseases and International Medicine Image Credit: University of Minnesota While doctors are still trying to better understand how to treat some of the most severe cases of COVID-19, researchers are looking at their current scientific "toolkit" to see if … Continue reading Therapy developed with CIRM award used in new clinical trial for COVID-19
CIRM progression award to support research towards immunodeficiency
Dr. Caroline Kuo, a member of the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA In 2017, CIRM funded a discovery or early stage research project for Dr. Caroline Kuo at UCLA for a hereditary immune disorder known as X-Linked Hyper IgM Syndrome. The work has gone so well … Continue reading CIRM progression award to support research towards immunodeficiency
Unproven “stem cell” therapy injuries are more common than we realized
Jaime Imitola, senior author of the paper and director of the Comprehensive Multiple Sclerosis Center at UConn Health Here at CIRM we only fund clinical trials that meet the rigorous standards outlined by the Food and Drug Administration (FDA). These requirements are not only necessary to properly evaluate how effective a potential treatment may be, … Continue reading Unproven “stem cell” therapy injuries are more common than we realized
CIRM Board Approves Two New Discovery Research Projects for COVID-19
Dr. Karen Christman (left) and Dr. Lili Yang (right) This past Friday the governing Board of the California Institute for Regenerative Medicine (CIRM) approved two new discovery research project as part of the $5 million in emergency funding for COVID-19 related projects. This brings the number of COVID-19 projects CIRM is supporting to 17, including three clinical trials. … Continue reading CIRM Board Approves Two New Discovery Research Projects for COVID-19
Magnetized stem cells used to treat lung disease in mice
Magnetic targeting technique has emerged as a new strategy to aid delivery, increase retention, and enhance the effects of mesenchymal stromal cells (MSCs) but, so far, has not been performed in lung diseases. With the aid of magnets, magnetized MSCs remained longer in the lungs, and this was associated with increased beneficial effects for the … Continue reading Magnetized stem cells used to treat lung disease in mice
The Stem Cellar 