Easier, Cheaper Stem Cell-Based Heart Muscle Sets Stage for Large-Scale Drug Development

The great inventions – like the automobile, the Internet or aviation – are marked as important turning points in human history. But it’s usually the additional tinkering that goes on in the ensuing years after the initial invention that makes the technology feasible in terms of cost, reproducibility and mass production. The same holds true … Continue reading Easier, Cheaper Stem Cell-Based Heart Muscle Sets Stage for Large-Scale Drug Development

How transcription factors and a healthy heart

Scientists at the Gladstone Institutes have discovered how a group of transcription factors interact during embryonic development to form a healthy heart. Their findings deepen our understanding of heart formation and may lead to new treatments for cardiovascular disease. The study, published today in the journal Cell, describes how cardiac transcription factors work together. Transcription … Continue reading How transcription factors and a healthy heart

Regenerating damaged heart muscle attack

Images of clusters of heart muscle cells (in red and green) derived from human embryonic stem cells 40 days after transplantation. Courtesy UCLA CIRM-funded researchers at UCLA have identified a way that could help regenerate damaged heart muscle, potentially not only saving lives of who've had heart attacks. Heart attacks Every year more than 735,000 … Continue reading Regenerating damaged heart muscle attack