Photo Courtesy of Andrea Fernandez de Soto Imagine a life where every time you step outside, everything in your environment poses a life-threatening risk. For children born with ADA-SCID (adenosine deaminase severe combined immunodeficiency), this is a reality. Their immune systems are so compromised that a common cold or a simple scrape on the knee … Continue reading Gene Therapy Brings Hope to Families Affected by Rare Immune Disorder
A Step Forward in the Fight Against Advanced Kidney Cancer
Photo Courtesy: Allogene Therapeutics Metastatic renal cell carcinoma (RCC) is an advanced form of kidney cancer with few treatment options and a five-year survival rate of less than 17%. With funding support from CIRM, Allogene Therapeutics is developing ALLO-316, an allogeneic CAR-T cell therapy which targets CD70—a protein highly expressed on clear cell renal cell … Continue reading A Step Forward in the Fight Against Advanced Kidney Cancer
Two CIRM-funded research projects receive RMAT designation from FDA
The U.S. Food and Drug Administration (FDA) has granted Regenerative Medicine Advanced Therapy (RMAT) designation to two research projects funded by the California Institute for Regenerative Medicine (CIRM). RMAT is a fast-track designation that can help speed up the development, review, and potential approval of treatments for serious or life-threatening diseases. The first RMAT designation … Continue reading Two CIRM-funded research projects receive RMAT designation from FDA
Remembering CIRM board member and ALS patient advocate Fred Fisher
CIRM would like to honor the contributions of Fred Fisher, MSW, LCSW, a dedicated member of our Independent Citizens’ Oversight Committee (ICOC) governing board and an enthusiastic patient advocate. Fred passed away in September. Fred joined the CIRM ICOC as the ALS patient advocate in June 2021 and held various roles during his tenure, including … Continue reading Remembering CIRM board member and ALS patient advocate Fred Fisher
Celebrating 20 Years of Progress: CIRM’s 2024 Annual Report is Now Available
This year marks an important milestone for the California Institute for Regenerative Medicine (CIRM)—20 years of accelerating innovation in regenerative medicine. To celebrate this achievement, we are excited to release the 2024 Annual Report, “Our Journey Forward: How CIRM Catalyzes Regenerative Medicine Today and Beyond.” For two decades, CIRM has played a pivotal role in … Continue reading Celebrating 20 Years of Progress: CIRM’s 2024 Annual Report is Now Available
CIRM Welcomes New Board Members
The California Institute for Regenerative Medicine (CIRM) is thrilled to welcome a distinguished group of new board members and alternates, each bringing a wealth of experience and leadership in healthcare, research, and innovation. Joyce A. Sackey, MD, FACP Dr. Sackey joins CIRM as an alternate for Linda Boxer. As the inaugural Chief Equity, Diversity, and … Continue reading CIRM Welcomes New Board Members
UCLA researchers exploring ways to prevent heart failure after heart attacks
ENPP1 is expressed in the region of scarring after injury to the heart. Cardiac muscle shown in red and ENPP1 in green demonstrates expression of ENPP1 in the region of scar formation. | Credit: Arjun Deb Lab/UCLA At the California Institute for Regenerative Medicine (CIRM), we support groundbreaking cardiovascular research from Discovery to Clinical as … Continue reading UCLA researchers exploring ways to prevent heart failure after heart attacks
How California is advancing our understanding of Alzheimer’s disease using stem cells
Over 14,000 people in Fresno County are living with Alzheimer's, and it’s estimated that more than 720,000 people are living with the brain disorder in California. That’s why the California Institute for Regenerative Medicine (CIRM)—a state of California agency dedicated to funding regenerative medicine research—joined the Alzheimer's Association Walk to End Alzheimer’s in Fresno/Madera to … Continue reading How California is advancing our understanding of Alzheimer’s disease using stem cells
CIRM Showcases Strategic Vision and New Initiatives at 7th Annual Alpha Clinics Network Symposium
Leveraging CIRM Infrastructure to Improve Accessibility Panel - From left to right: Noah Federman, MD (moderator), Catriona Jamieson, MD, PhD, Mehrdad Abedi, MD, Daniela Bota, MD, PhD, Thomas Buchanan, MD, Brian Fury, MS, Dhruv Sareen, PhD, and Taby Ahsan, PhD The California Institute for Regenerative Medicine (CIRM) recently sponsored the 7th Annual CIRM Alpha Clinics … Continue reading CIRM Showcases Strategic Vision and New Initiatives at 7th Annual Alpha Clinics Network Symposium
Story of Hope: Elpida Therapeutics’ Pioneer Study on Rare Nerve Disease CMT4J
Image source: SickKids -Terry, Georgia, and Michael Pirovolakis CIRM awarded Elpida Therapeutics a $3.9 million grant in December 2023 to support a pioneering preclinical study on Charcot Marie Tooth disease type 4J (CMT4J). CMT4J is an ultra-rare, inherited condition that primarily affects the nerves outside the brain and spinal cord. It accounts for about 0.24% … Continue reading Story of Hope: Elpida Therapeutics’ Pioneer Study on Rare Nerve Disease CMT4J
The Stem Cellar 