Multilayer retinina created from embryonic stem cells

More news from UC Irvine, this time relating to retinal diseases such as macular degeneration, retinitis pigmentosa, and Stargardt’s disease. A group led by Hans Keirstead of the Reeve-Irvine Research Center and the Sue & Bill Gross Stem Cell Research Center created an 8-layer retina from human embryonic stem cells.In a press release, Keirstead said:“What’s … Continue reading Multilayer retinina created from embryonic stem cells

Mysteries of stem cell migration revealed

CIRM-funded Researchers at the University of California, Irvine published an interesting paper this week that helps explain one mystery — how do transplanted stem cells go to the right place? This is an important issue for diseases such as multiple sclerosis, where transplanted stem cells would have to navigate to the damaged nerves.In a press … Continue reading Mysteries of stem cell migration revealed

Stem cell therapies: Not just transplants

Paul Knoepfler, a CIRM grantee at UC Davis, has a recent blog entry in his Stem Cell Myths series. The myth he debunks this time: Stem cell therapies are all transplants. As he so rightly points out, embryonic, iPS or tissue-specific stem cells can also be studied in the lab as a way of developing … Continue reading Stem cell therapies: Not just transplants

Stem cell banking workshop explores ethical and policy issues

At the 2010 Stem Cell Banking Workshop on May 26, CIRM president Alan Trounson discussed the potential value of a cell bank designed to support the needs of researchers and industry. Many of the participants believe there would be great scientific value in a bank that could provide a common approach to cell collection and … Continue reading Stem cell banking workshop explores ethical and policy issues

Between Mice and Men, a New Type of Stem Cell

Humans and other non-human primates stand out from their fellow mammals in many ways, but notably by having one particularly oversized area of the brain. This area, the outer subventricular zone (OSVZ) feeds migrating neurons to the neocortex the seat of sensory perception, spatial reasoning, conscious thought and language. Scientists always assumed the OSVZ must … Continue reading Between Mice and Men, a New Type of Stem Cell

iPS cells and embryonic stem cells — similar but not the same

In the most recent face-off between iPS and embryonic stem cells, the ES cells came out ahead -- turns out iPS cells aren't the same as ES cells even when they carry the same mutation. That's according to work published in the May 7 issue of Cell Stem Cell.(The image shows colonies of embryonic and … Continue reading iPS cells and embryonic stem cells — similar but not the same

UC Irvine Opens the Sue & Bill Gross Hall

On Friday, May 14 UC Irvine held the grand opening of their newly constructed Sue &Bill Gross Hall. According to a story on the University's web site:The $80-million, 100,000-square-foot building was designed to facilitate contact between patients in the first-floor clinic and rehabilitation center and stem cell researchers in first-, second- and third-floor labs.(Image: Hans … Continue reading UC Irvine Opens the Sue & Bill Gross Hall

Hairs in a Dish Give Hope to Damaged Ears

The microscopic hair cells found in the inner ear are so sensitive to vibration they can relay to the brain whether the air movement around them is from guitar licks by Eric Clapton or a piano chord from a Chopin Palinais, but too many loud Metallica concerts can damage them leading to hearing loss. Now, … Continue reading Hairs in a Dish Give Hope to Damaged Ears

NIH accepts new human embryonic stem cell lines

By Geoff Lomax The NIH has accepted three new human embryonic stem cell lines, created by CIRM grantee Amander Clark at UCLA. According to the UCLA press release:“The addition of the three human embryonic stem cells lines to the registry brings the total number of lines available for federal funding to 64, NIH officials said. … Continue reading NIH accepts new human embryonic stem cell lines

Questions About iPS Cells

In his blog, CIRM grantee Paul Knoepfler at UC Davis posted a response to the journal Stem Cells, which had published a list of the most pressing questions about iPS cells:“What I found most striking is that not one of their 10 questions had anything to do with safety or tumorigenicity, the question I rank … Continue reading Questions About iPS Cells