How CIRM contributed to City of Hope study helping man with HIV into long-term remission

The news that a stem cell transplant at City of Hope helped a man with HIV go into long-term remission made banner headlines around the world. As it should. It’s a huge achievement, particularly as the 66-year-old man had been living with HIV since 1988. What wasn’t reported was that work supported by the California … Continue reading How CIRM contributed to City of Hope study helping man with HIV into long-term remission

An experimental gene therapy with a hairy twist

In October 2019, 20-year-old Jordan Janz became the first person in the world to receive an experimental therapy for cystinosis. Cystinosis is a rare genetic disorder characterized by the accumulation of an amino acid called cystine in different tissues and organs of the body including the kidneys, eyes, muscles, liver, pancreas, and brain. This accumulation … Continue reading An experimental gene therapy with a hairy twist

Stem Cell Agency Board Invests in 19 Discovery Research Programs Targeting Cancers, Heart Disease and Other Disorders

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Dr. Judy Shizuru, Stanford University While stem cell and gene therapy research has advanced dramatically in recent years, there are still many unknowns and many questions remaining about how best to use these approaches in developing therapies. That’s why the governing Board of the California Institute … Continue reading Stem Cell Agency Board Invests in 19 Discovery Research Programs Targeting Cancers, Heart Disease and Other Disorders

Meet the man who is unlocking the secrets of autism and sending mini-brains into space

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Dr. Alysson Muotri, UC San Diego Normally if you meet someone who has a mini-fridge filled with brains, your first thought is to call the police. But when that someone is Dr. Alysson Muotri, a professor at U.C. San Diego, your second thought is “do tell … Continue reading Meet the man who is unlocking the secrets of autism and sending mini-brains into space

CIRM Board gives thumbs up to training and treatment programs

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST CIRM Bridges student discusses her poster presentation At CIRM, the bread and butter of what we do is funding research and hopefully advancing therapies to patients. But the jam, that's our education programs. Helping train the next generation of stem cell and gene therapy scientists is … Continue reading CIRM Board gives thumbs up to training and treatment programs

Two Early-Stage Research Programs Targeting Cartilage Damage Get Funding from Stem Cell Agency

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Darryl D'Lima: Scripps Health Every year millions of Americans suffer damage to their cartilage, either in their knee or other joints, that can eventually lead to osteoarthritis, pain and immobility. Today the governing Board of the California Institute for Regenerative Medicine (CIRM) approved two projects targeting … Continue reading Two Early-Stage Research Programs Targeting Cartilage Damage Get Funding from Stem Cell Agency

Breaking down barriers: Expanding patient access and accelerating research

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST 10 years ago I was presented with an incredibly unique opportunity- to become the fifth patient with spinal cord injuries to participate in the world's first clinical trial testing a treatment made from human embryonic stem cells. It was not only a risky and potentially life-changing decision, … Continue reading Breaking down barriers: Expanding patient access and accelerating research

Stem Cell Agency Board Invests in Therapy Targeting Deadly Blood Cancers

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Dr. Ezra Cohen, photo courtesy UCSD Hematologic malignancies are cancers that affect the blood, bone marrow and lymph nodes and include different forms of leukemia and lymphoma. Current treatments can be effective, but in those patients that do not respond, there are few treatment options. Today, … Continue reading Stem Cell Agency Board Invests in Therapy Targeting Deadly Blood Cancers

Creating a diverse group of future scientists

Students in CIRM's Bridges program showing posters of their work If you have read the headlines lately, you’ll know that the COVID-19 pandemic is having a huge impact on the shipping industry. Container vessels are forced to sit out at anchor for a week or more because there just aren’t enough dock workers to unload … Continue reading Creating a diverse group of future scientists

Retooling a COVID drug to boost its effectiveness

Coronavirus particles, illustration. When the COVID-19 pandemic broke out scientists scrambled to find existing medications that might help counter the life-threatening elements of the virus. One of the first medications that showed real promise was remdesivir. It’s an anti-viral drug that was originally developed to target novel, emerging viruses, viruses like COVID19. It was approved … Continue reading Retooling a COVID drug to boost its effectiveness