Stem cell therapy may help mend a broken heart

Blausen.com staff (2014). "Medical gallery of Blausen Medical 2014 Dilated cardiomyopathy (DCM), a condition where the muscles of the heart are weak and can lead to heart failure, is considered rare in children. However, because the symptoms are not always easy to recognize the condition can go unnoticed for many years, and in severe cases … Continue reading Stem cell therapy may help mend a broken heart

Celebrating a young life that almost wasn’t

Often on the Stem Cellar we feature CIRM-funded work that is helping advance the field, unlocking some of the secrets of stem cells and how best to use them to develop promising therapies. But every once in a while it’s good to remind ourselves that this work, while it may often seem slow, is already … Continue reading Celebrating a young life that almost wasn’t

Learning life lessons in the lab

Rohan Upadhyay, CIRM SPARK student 2021 One of the most amazing parts of an amazing job is getting to know the students who take part in CIRM’s SPARK (Summer Program to Accelerate Regenerative Medicine Knowledge) program. It’s an internship giving high school students, that reflect the diversity of California, a chance to work in a … Continue reading Learning life lessons in the lab

Retooling a COVID drug to boost its effectiveness

Coronavirus particles, illustration. When the COVID-19 pandemic broke out scientists scrambled to find existing medications that might help counter the life-threatening elements of the virus. One of the first medications that showed real promise was remdesivir. It’s an anti-viral drug that was originally developed to target novel, emerging viruses, viruses like COVID19. It was approved … Continue reading Retooling a COVID drug to boost its effectiveness

How regrowing tiny hairs could restore hearing loss

Man getting fitted with hearing aids Hearing loss is something that affect tens of millions of Americans. Usually people notice those changes as they get older but the damage can be done years before that through the use of some prescription drugs or exposure to loud noise (I knew I shouldn’t have sat in the … Continue reading How regrowing tiny hairs could restore hearing loss

Gene therapy is life-changing for children with a life-threatening brain disorder

If you have never heard of AADC deficiency count yourself lucky. It’s a rare, incurable condition that affects only around 135 children worldwide but it’s impact on those children and their families is devastating. The children can’t speak, can’t feed themselves or hold up their head, they have severe mood swings and often suffer from … Continue reading Gene therapy is life-changing for children with a life-threatening brain disorder

Hollywood and Patient Advocacy – two people who are on our Board but never boring

At first glance, Lauren Miller Rogen and David Higgins, PhD, seem an unlikely pair. She’s an actor, writer, and director and has worked with some of the biggest names in Hollywood. He has a doctorate in molecular biology and genetics and has worked at some of the most well-known companies in biotech. But together they … Continue reading Hollywood and Patient Advocacy – two people who are on our Board but never boring

Sometimes a cold stare is a good thing

A retina of a patient with macular degeneration. (Photo credit: Paul Parker/SPL) Age-related macular degeneration (AMD) is the leading cause of vision loss and blindness in the elderly in the U.S. It’s estimated that some 11 million Americans could have some form of the disease, a number that is growing every year. So if you … Continue reading Sometimes a cold stare is a good thing

Paving the Way

When someone scores a goal in soccer all the attention is lavished on them. Fans chant their name, their teammates pile on top in celebration, their agent starts calling sponsors asking for more money. But there’s often someone else deserving of praise too, that’s the player who provided the assist to make the goal possible … Continue reading Paving the Way

How stem cells play “follow the leader”

Todd McDevitt, PhD Photo courtesy: Gladstone Institutes It’s hard enough trying to follow the movements of individuals in a crowd of people, but imagine how much harder it is to follow the movements of stem cells crowded into a tiny petri dish. Well, researchers at the Gladstone Institutes in San Francisco have done just that. … Continue reading How stem cells play “follow the leader”