What happens in a stroke When someone has a stroke, the blood flow to the brain is blocked. This kills some nerve cells and injures others. The damaged nerve cells are unable to communicate with other cells, which often results in people having impaired speech or movement. While ischemic and hemorrhagic strokes affect large blood … Continue reading Paving the way for a treatment for dementia
CIRM News
Learning life lessons in the lab
Rohan Upadhyay, CIRM SPARK student 2021 One of the most amazing parts of an amazing job is getting to know the students who take part in CIRM’s SPARK (Summer Program to Accelerate Regenerative Medicine Knowledge) program. It’s an internship giving high school students, that reflect the diversity of California, a chance to work in a … Continue reading Learning life lessons in the lab
SPARKing the genius of the next generation of scientists
Dr. Kelly Shepard, SPARK program director After almost 18 months – and counting – that have put us all to the test, made us wear masks, work from home, limit contact with all but the closest of family and friends it’s a wonderful thing to be able to get a glimpse of the future and … Continue reading SPARKing the genius of the next generation of scientists
A conversation with Bob Klein about the past, present, and future of CIRM
Bob Klein Anyone who knows anything about CIRM knows about Bob Klein. He's the main author and driving force behind both Proposition 71 and Proposition 14, the voter-approved ballot initiatives that first created and then refunded CIRM. It's safe to say that without Bob, there'd be no CIRM. Recently, we had the great good fortune … Continue reading A conversation with Bob Klein about the past, present, and future of CIRM
Retooling a COVID drug to boost its effectiveness
Coronavirus particles, illustration. When the COVID-19 pandemic broke out scientists scrambled to find existing medications that might help counter the life-threatening elements of the virus. One of the first medications that showed real promise was remdesivir. It’s an anti-viral drug that was originally developed to target novel, emerging viruses, viruses like COVID19. It was approved … Continue reading Retooling a COVID drug to boost its effectiveness
A rare chance to help those in need
Recently the CIRM Board voted to support the creation of a Rare Disease Advisory Council (RDAC) in California. An RDAC is an advisory body providing a platform for the rare community to have a stronger voice in state government. They address the needs of rare patients and families by giving stakeholders an opportunity to make … Continue reading A rare chance to help those in need
Gene therapy is life-changing for children with a life-threatening brain disorder
If you have never heard of AADC deficiency count yourself lucky. It’s a rare, incurable condition that affects only around 135 children worldwide but it’s impact on those children and their families is devastating. The children can’t speak, can’t feed themselves or hold up their head, they have severe mood swings and often suffer from … Continue reading Gene therapy is life-changing for children with a life-threatening brain disorder
Hollywood and Patient Advocacy – two people who are on our Board but never boring
At first glance, Lauren Miller Rogen and David Higgins, PhD, seem an unlikely pair. She’s an actor, writer, and director and has worked with some of the biggest names in Hollywood. He has a doctorate in molecular biology and genetics and has worked at some of the most well-known companies in biotech. But together they … Continue reading Hollywood and Patient Advocacy – two people who are on our Board but never boring
We’ve got cash, here’s how you can get some
When the voters of California approved Proposition 14 last November (thanks folks) they gave us $5.5 billion to continue the work we started way back in 2014. It’s a great honor, and a great responsibility. It’s also a great opportunity to look at what we do and how we do it and try to come … Continue reading We’ve got cash, here’s how you can get some
Heads or tails? Stem cells help guide the decision
Two cell embryo There are many unknown elements for what triggers the cells in an embryo to start dividing and multiplying and becoming every single cell in the body. Now researchers at the Gladstone Institutes in San Francisco have uncovered one of those elements, how embryos determine which cells become the head and which the … Continue reading Heads or tails? Stem cells help guide the decision