Dr. Charles K.F. Chan (Left) and Dr. Michael Longaker (right), Stanford University Cartilage is a flexible, connective tissue in our joints that is important for cushioning our bones against impacts. This cartilage deteriorates as we age due to normal wear and tear and in some instances excessive damage or a deteriorating disease. The deterioration of … Continue reading Researchers discover how to steer stem cells to regenerate cartilage in joints
Bone/Muscle/Blood
Stem Cell All-Stars, All For You
Dr. Larry Goldstein, UC San Diego It’s not often you get a chance to hear some of the brightest minds around talk about their stem cell research and what it could mean for you, me and everyone else. That’s why we’re delighted to be bringing some of the sharpest tools in the stem cell shed … Continue reading Stem Cell All-Stars, All For You
Stem cells used to promote quick and precise bone healing
A close-up view of the intricate microarchitecture of the pluripotent stem-cell-derived extracellular matrix. Image Credit: Carl Gregory/Texas A&M Although some broken bones can be mended with the help of a cast, others require more complex treatments. Bone grafts, which can come from the patient's own body or a donor, are used to transplant bone tissue … Continue reading Stem cells used to promote quick and precise bone healing
Promising results from CIRM-funded projects
Severe Leukocyte Adhesion Deficiency-1 (LAD-1) is a rare condition that causes the immune system to malfunction and reduces its ability to fight off viruses and bacteria. Over time the repeated infections can take a heavy toll on the body and dramatically shorten a person’s life. But now a therapy, developed by Rocket Pharmaceuticals, is showing … Continue reading Promising results from CIRM-funded projects
You can bank on CIRM
Way back in 2013, the CIRM Board invested $32 million in a project to create an iPSC Bank. The goal was simple; to collect tissue samples from people who have different diseases, turn those samples into high quality stem cell lines - the kind known as induced pluripotent stem cells (iPSC) - and create a … Continue reading You can bank on CIRM
Breakthrough image could lead to better therapies
Image of a blood stem cell in its natural environment: Photo courtesy UC Merced When it comes to using stem cells for therapy you don’t just need to understand what kinds of cell to use, you also need to understand the environment that is best for them. Trying to get stem cells to grow in … Continue reading Breakthrough image could lead to better therapies
Two CIRM supported studies highlighted in Nature as promising approaches for blood disorders
Blood stem cells (blue) are cleared from the bone marrow (purple) before new stem cells can be transplanted.Credit: Dennis Kunkel Microscopy/SPL Problems with blood stem cells, a type of stem cell in your bone marrow that gives rise to various kinds of blood cells, can sometimes result in blood cancer as well as genetic and … Continue reading Two CIRM supported studies highlighted in Nature as promising approaches for blood disorders
Researchers create a better way to grow blood stem cells
UCLA's Dr. Hanna Mikkola and Vincenzo Calvanese, lead scientists on the study. Photo courtesy UCLA Blood stem cells are a vital part of us. They create all the other kinds of blood cells in our body and are used in bone marrow transplants to help people battling leukemia or other blood cancers. The problem is … Continue reading Researchers create a better way to grow blood stem cells
How early CIRM support helped an anti-cancer therapy overcome obstacles and help patients
Dr. Catriona Jamieson, UC San Diego When you read about a new drug or therapy being approved to help patients it always seems so simple. Researchers come up with a brilliant idea, test it to make sure it is safe and works, and then get approval from the US Food and Drug Administration (FDA) to … Continue reading How early CIRM support helped an anti-cancer therapy overcome obstacles and help patients
CIRM funded research could lead to treatment to prevent recurrence of deadly blood cancer
Chronic myelogenous leukemia Chronic myelogenous leukemia (CML) is a cancer of the white blood cells. It causes them to increase in number, crowd out other blood cells, leading to anemia, infection or heavy bleeding. Up until the early 2000’s the main weapon against CML was chemotherapy, but the introduction of drugs called tyrosine kinase inhibitors … Continue reading CIRM funded research could lead to treatment to prevent recurrence of deadly blood cancer